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Capsuloganglionic Germinoma: A Rare Site for Uncommon Childhood Tumor

Germ cell tumors (GCTs) are rare intracranial tumors with a strong predilection for children. Commonly, these tumors arise either in the suprasellar or the pineal region. The basal ganglia-thalamus complex represents a rare site of nonmidline intracranial GCTs. Such basal ganglionic GCTs have been r...

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Detalles Bibliográficos
Autores principales: Das, Kuntal Kanti, Joseph, Jeena, Singh, Amit Kumar, Sharma, Pradeep, Sardhara, Jayesh, Bhaisora, Kamlesh Singh, Mehrotra, Anant, Srivastava, Arun Kumar, Jaiswal, Sushila, Sahu, Rabi Narayan, Jaiswal, Awadhesh Kumar, Behari, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898141/
https://www.ncbi.nlm.nih.gov/pubmed/29682070
http://dx.doi.org/10.4103/ajns.AJNS_284_16
Descripción
Sumario:Germ cell tumors (GCTs) are rare intracranial tumors with a strong predilection for children. Commonly, these tumors arise either in the suprasellar or the pineal region. The basal ganglia-thalamus complex represents a rare site of nonmidline intracranial GCTs. Such basal ganglionic GCTs have been reported to produce certain interesting clinico-radiological features, the knowledge of which may provide important diagnostic clues preoperatively. We present the case of a 9.5-year-old boy who presented with right hemiparesis and precocious puberty. Imaging revealed a heterogeneously enhancing mass involving the left capsuloganglionic region, sparing the thalamus. There was little perilesional edema and midline shift. Because of the deep location of the mass and a lack of mass effect, a neuronavigation-guided tumor biopsy was performed which unraveled a pure germinoma. The child was referred for adjuvant radiotherapy following an uneventful postoperative course. At the time of writing the report, the child was on radiotherapy and doing well.