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Capsuloganglionic Germinoma: A Rare Site for Uncommon Childhood Tumor

Germ cell tumors (GCTs) are rare intracranial tumors with a strong predilection for children. Commonly, these tumors arise either in the suprasellar or the pineal region. The basal ganglia-thalamus complex represents a rare site of nonmidline intracranial GCTs. Such basal ganglionic GCTs have been r...

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Autores principales: Das, Kuntal Kanti, Joseph, Jeena, Singh, Amit Kumar, Sharma, Pradeep, Sardhara, Jayesh, Bhaisora, Kamlesh Singh, Mehrotra, Anant, Srivastava, Arun Kumar, Jaiswal, Sushila, Sahu, Rabi Narayan, Jaiswal, Awadhesh Kumar, Behari, Sanjay
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898141/
https://www.ncbi.nlm.nih.gov/pubmed/29682070
http://dx.doi.org/10.4103/ajns.AJNS_284_16
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author Das, Kuntal Kanti
Joseph, Jeena
Singh, Amit Kumar
Sharma, Pradeep
Sardhara, Jayesh
Bhaisora, Kamlesh Singh
Mehrotra, Anant
Srivastava, Arun Kumar
Jaiswal, Sushila
Sahu, Rabi Narayan
Jaiswal, Awadhesh Kumar
Behari, Sanjay
author_facet Das, Kuntal Kanti
Joseph, Jeena
Singh, Amit Kumar
Sharma, Pradeep
Sardhara, Jayesh
Bhaisora, Kamlesh Singh
Mehrotra, Anant
Srivastava, Arun Kumar
Jaiswal, Sushila
Sahu, Rabi Narayan
Jaiswal, Awadhesh Kumar
Behari, Sanjay
author_sort Das, Kuntal Kanti
collection PubMed
description Germ cell tumors (GCTs) are rare intracranial tumors with a strong predilection for children. Commonly, these tumors arise either in the suprasellar or the pineal region. The basal ganglia-thalamus complex represents a rare site of nonmidline intracranial GCTs. Such basal ganglionic GCTs have been reported to produce certain interesting clinico-radiological features, the knowledge of which may provide important diagnostic clues preoperatively. We present the case of a 9.5-year-old boy who presented with right hemiparesis and precocious puberty. Imaging revealed a heterogeneously enhancing mass involving the left capsuloganglionic region, sparing the thalamus. There was little perilesional edema and midline shift. Because of the deep location of the mass and a lack of mass effect, a neuronavigation-guided tumor biopsy was performed which unraveled a pure germinoma. The child was referred for adjuvant radiotherapy following an uneventful postoperative course. At the time of writing the report, the child was on radiotherapy and doing well.
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spelling pubmed-58981412018-04-20 Capsuloganglionic Germinoma: A Rare Site for Uncommon Childhood Tumor Das, Kuntal Kanti Joseph, Jeena Singh, Amit Kumar Sharma, Pradeep Sardhara, Jayesh Bhaisora, Kamlesh Singh Mehrotra, Anant Srivastava, Arun Kumar Jaiswal, Sushila Sahu, Rabi Narayan Jaiswal, Awadhesh Kumar Behari, Sanjay Asian J Neurosurg Case Report Germ cell tumors (GCTs) are rare intracranial tumors with a strong predilection for children. Commonly, these tumors arise either in the suprasellar or the pineal region. The basal ganglia-thalamus complex represents a rare site of nonmidline intracranial GCTs. Such basal ganglionic GCTs have been reported to produce certain interesting clinico-radiological features, the knowledge of which may provide important diagnostic clues preoperatively. We present the case of a 9.5-year-old boy who presented with right hemiparesis and precocious puberty. Imaging revealed a heterogeneously enhancing mass involving the left capsuloganglionic region, sparing the thalamus. There was little perilesional edema and midline shift. Because of the deep location of the mass and a lack of mass effect, a neuronavigation-guided tumor biopsy was performed which unraveled a pure germinoma. The child was referred for adjuvant radiotherapy following an uneventful postoperative course. At the time of writing the report, the child was on radiotherapy and doing well. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5898141/ /pubmed/29682070 http://dx.doi.org/10.4103/ajns.AJNS_284_16 Text en Copyright: © 2018 Asian Journal of Neurosurgery http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Das, Kuntal Kanti
Joseph, Jeena
Singh, Amit Kumar
Sharma, Pradeep
Sardhara, Jayesh
Bhaisora, Kamlesh Singh
Mehrotra, Anant
Srivastava, Arun Kumar
Jaiswal, Sushila
Sahu, Rabi Narayan
Jaiswal, Awadhesh Kumar
Behari, Sanjay
Capsuloganglionic Germinoma: A Rare Site for Uncommon Childhood Tumor
title Capsuloganglionic Germinoma: A Rare Site for Uncommon Childhood Tumor
title_full Capsuloganglionic Germinoma: A Rare Site for Uncommon Childhood Tumor
title_fullStr Capsuloganglionic Germinoma: A Rare Site for Uncommon Childhood Tumor
title_full_unstemmed Capsuloganglionic Germinoma: A Rare Site for Uncommon Childhood Tumor
title_short Capsuloganglionic Germinoma: A Rare Site for Uncommon Childhood Tumor
title_sort capsuloganglionic germinoma: a rare site for uncommon childhood tumor
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898141/
https://www.ncbi.nlm.nih.gov/pubmed/29682070
http://dx.doi.org/10.4103/ajns.AJNS_284_16
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