Cargando…

The Effect of Elevated A1C on Immediate Postoperative Complications: A Prospective Observational Study

IN BRIEF This study examined whether elevated A1C in patients with diabetes is associated with a higher incidence of postoperative infections and other complications. Researchers followed 50 noncardiac surgical patients for 7 postoperative days. Half of the patients had an A1C <7% and the other h...

Descripción completa

Detalles Bibliográficos
Autores principales: Chen, Pinxia, Hallock, Katherine K., Mulvey, Christie L., Berg, Arthur S., Cherian, Verghese T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898174/
https://www.ncbi.nlm.nih.gov/pubmed/29686451
http://dx.doi.org/10.2337/cd17-0081
_version_ 1783314090371842048
author Chen, Pinxia
Hallock, Katherine K.
Mulvey, Christie L.
Berg, Arthur S.
Cherian, Verghese T.
author_facet Chen, Pinxia
Hallock, Katherine K.
Mulvey, Christie L.
Berg, Arthur S.
Cherian, Verghese T.
author_sort Chen, Pinxia
collection PubMed
description IN BRIEF This study examined whether elevated A1C in patients with diabetes is associated with a higher incidence of postoperative infections and other complications. Researchers followed 50 noncardiac surgical patients for 7 postoperative days. Half of the patients had an A1C <7% and the other half had an A1C ≥7%. The two groups were otherwise comparable except that the higher-A1C group had significantly higher pre-induction and postoperative blood glucose levels, with wider variability in the first 24 hours after surgery. During the first postoperative week, 11 patients developed complications, of whom 10 were in the higher-A1C group. Elevated A1C, unlike a single preoperative blood glucose value, may predict difficult postoperative glucose control and postsurgical complications.
format Online
Article
Text
id pubmed-5898174
institution National Center for Biotechnology Information
language English
publishDate 2018
publisher American Diabetes Association
record_format MEDLINE/PubMed
spelling pubmed-58981742019-04-01 The Effect of Elevated A1C on Immediate Postoperative Complications: A Prospective Observational Study Chen, Pinxia Hallock, Katherine K. Mulvey, Christie L. Berg, Arthur S. Cherian, Verghese T. Clin Diabetes Feature Articles IN BRIEF This study examined whether elevated A1C in patients with diabetes is associated with a higher incidence of postoperative infections and other complications. Researchers followed 50 noncardiac surgical patients for 7 postoperative days. Half of the patients had an A1C <7% and the other half had an A1C ≥7%. The two groups were otherwise comparable except that the higher-A1C group had significantly higher pre-induction and postoperative blood glucose levels, with wider variability in the first 24 hours after surgery. During the first postoperative week, 11 patients developed complications, of whom 10 were in the higher-A1C group. Elevated A1C, unlike a single preoperative blood glucose value, may predict difficult postoperative glucose control and postsurgical complications. American Diabetes Association 2018-04 /pmc/articles/PMC5898174/ /pubmed/29686451 http://dx.doi.org/10.2337/cd17-0081 Text en © 2017 by the American Diabetes Association. Readers may use this article as long as the work is properly cited, the use is educational and not for profit, and the work is not altered. See http://creativecommons.org/licenses/by-nc-nd/3.0 for details.
spellingShingle Feature Articles
Chen, Pinxia
Hallock, Katherine K.
Mulvey, Christie L.
Berg, Arthur S.
Cherian, Verghese T.
The Effect of Elevated A1C on Immediate Postoperative Complications: A Prospective Observational Study
title The Effect of Elevated A1C on Immediate Postoperative Complications: A Prospective Observational Study
title_full The Effect of Elevated A1C on Immediate Postoperative Complications: A Prospective Observational Study
title_fullStr The Effect of Elevated A1C on Immediate Postoperative Complications: A Prospective Observational Study
title_full_unstemmed The Effect of Elevated A1C on Immediate Postoperative Complications: A Prospective Observational Study
title_short The Effect of Elevated A1C on Immediate Postoperative Complications: A Prospective Observational Study
title_sort effect of elevated a1c on immediate postoperative complications: a prospective observational study
topic Feature Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898174/
https://www.ncbi.nlm.nih.gov/pubmed/29686451
http://dx.doi.org/10.2337/cd17-0081
work_keys_str_mv AT chenpinxia theeffectofelevateda1conimmediatepostoperativecomplicationsaprospectiveobservationalstudy
AT hallockkatherinek theeffectofelevateda1conimmediatepostoperativecomplicationsaprospectiveobservationalstudy
AT mulveychristiel theeffectofelevateda1conimmediatepostoperativecomplicationsaprospectiveobservationalstudy
AT bergarthurs theeffectofelevateda1conimmediatepostoperativecomplicationsaprospectiveobservationalstudy
AT cherianvergheset theeffectofelevateda1conimmediatepostoperativecomplicationsaprospectiveobservationalstudy
AT chenpinxia effectofelevateda1conimmediatepostoperativecomplicationsaprospectiveobservationalstudy
AT hallockkatherinek effectofelevateda1conimmediatepostoperativecomplicationsaprospectiveobservationalstudy
AT mulveychristiel effectofelevateda1conimmediatepostoperativecomplicationsaprospectiveobservationalstudy
AT bergarthurs effectofelevateda1conimmediatepostoperativecomplicationsaprospectiveobservationalstudy
AT cherianvergheset effectofelevateda1conimmediatepostoperativecomplicationsaprospectiveobservationalstudy