A novel reporter allele for monitoring Dll4 expression within the embryonic and adult mouse

Canonical Notch signaling requires the presence of a membrane bound ligand and a corresponding transmembrane Notch receptor. Receptor engagement induces multiple proteolytic cleavage events culminating in the nuclear accumulation of the Notch intracellular domain and its binding to a transcriptional...

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Detalles Bibliográficos
Autores principales: Herman, Alexander M., Rhyner, Alexander M., Devine, W. Patrick, Marrelli, Sean P., Bruneau, Benoit G., Wythe, Joshua D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898260/
https://www.ncbi.nlm.nih.gov/pubmed/29437553
http://dx.doi.org/10.1242/bio.026799

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898260/
https://www.ncbi.nlm.nih.gov/pubmed/29437553
http://dx.doi.org/10.1242/bio.026799

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