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β-Catenin-driven adrenocortical carcinoma is characterized with immune exclusion

AIM: Adrenocortical carcinoma (ACC) is characterized by overexpressed CTNNB1, which is reported to modulate immune exclusion. Cross talk between CTNNB1 and cancer immunity in ACC remains unclear. MATERIALS AND METHODS: In silico reproduction of TCGA-ACC dataset (N = 92) and external validation using...

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Detalles Bibliográficos
Autores principales:	Liu, Shenghua, Ding, Guanxiong, Zhou, Zhongwen, Feng, Chenchen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2018
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898592/ https://www.ncbi.nlm.nih.gov/pubmed/29670378 http://dx.doi.org/10.2147/OTT.S159979

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