Cargando…

17β-Estradiol on the Expression of G-Protein Coupled Estrogen Receptor (GPER/GPR30) Mitophagy, and the PI3K/Akt Signaling Pathway in ATDC5 Chondrocytes In Vitro

BACKGROUND: Osteoarthritis is a progressive inflammatory joint disease resulting in damage to articular cartilage. G-protein coupled estrogen receptor (GPER/GPR30) activates cell signaling in response to 17β-estradiol, which can be blocked by the GPR30 agonist, G15, an analog of G-1. The aims of thi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Fan, Dong-xiao, Yang, Xu-hao, Li, Yi-nan, Guo, Lei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	International Scientific Literature, Inc. 2018
Materias:	Lab/In Vitro Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898603/ https://www.ncbi.nlm.nih.gov/pubmed/29608013 http://dx.doi.org/10.12659/MSM.909365

Ejemplares similares

Effects of 17β-Estradiol on Mitophagy in the Murine MC3T3-E1 Osteoblast Cell Line is Mediated via G Protein-Coupled Estrogen Receptor and the ERK1/2 Signaling Pathway
por: Sun, Xiaoqi, et al.
Publicado: (2018)

17β-Estradiol Inhibites Tumor Necrosis Factor-α Induced Apoptosis of Human Nucleus Pulposus Cells via the PI3K/Akt Pathway
por: Wang, Tao, et al.
Publicado: (2016)

Salidroside Suppresses IL-1β-Induced Apoptosis in Chondrocytes via Phosphatidylinositol 3-Kinases (PI3K)/Akt Signaling Inhibition
por: Wu, Mingzheng, et al.
Publicado: (2019)

G-protein Coupled Estrogen Receptor (GPER/GPR30) and Women's Health
por: Kim, Mi-Jin, et al.
Publicado: (2015)

17β-Estradiol Promotes Angiogenesis of Rat Cardiac Microvascular Endothelial Cells In Vitro
por: Liu, HaiTao, et al.
Publicado: (2018)

C(18)H(17)NO(6) Inhibits Invasion and Migration of Human MNNG Osteosarcoma Cells via the PI3K/AKT Signaling Pathway
por: Qu, Qianqian, et al.
Publicado: (2019)

Enhanced expression of G-protein coupled estrogen receptor (GPER/GPR30) in lung cancer
por: Jala, Venkatakrishna Rao, et al.
Publicado: (2012)

The G-Protein-Coupled Estrogen Receptor (GPER/GPR30) in Ovarian Granulosa Cell Tumors
por: Heublein, Sabine, et al.
Publicado: (2014)

Calycosin, a Phytoestrogen Isoflavone, Induces Apoptosis of Estrogen Receptor-Positive MG-63 Osteosarcoma Cells via the Phosphatidylinositol 3-Kinase (PI3K)/AKT/Mammalian Target of Rapamycin (mTOR) Pathway
por: Sun, Haitao, et al.
Publicado: (2018)

Effect of miR-106b on Invasiveness of Pituitary Adenoma via PTEN-PI3K/AKT
por: Zheng, Zhiming, et al.
Publicado: (2017)

Icariin Protects Mouse Insulinoma Min6 Cell Function by Activating the PI3K/AKT Pathway
por: Zhang, Tao, et al.
Publicado: (2020)

Ursolic Acid Attenuates High Glucose-Mediated Mesangial Cell Injury by Inhibiting the Phosphatidylinositol 3-Kinase/Akt/Mammalian Target of Rapamycin (PI3K/Akt/mTOR) Signaling Pathway
por: Wang, Er-Min, et al.
Publicado: (2018)

Albumin Overload and PINK1/Parkin Signaling-Related Mitophagy in Renal Tubular Epithelial Cells
por: Tan, Jin, et al.
Publicado: (2018)

Anticancer Effects of Paris Saponins by Apoptosis and PI3K/AKT Pathway in Gefitinib-Resistant Non-Small Cell Lung Cancer
por: Zhu, Xinhai, et al.
Publicado: (2016)

Irisin Enhances Doxorubicin-Induced Cell Apoptosis in Pancreatic Cancer by Inhibiting the PI3K/AKT/NF-κB Pathway
por: Liu, Jiayu, et al.
Publicado: (2019)

Wogonin Increases Cisplatin Sensitivity in Ovarian Cancer Cells Through Inhibition of the Phosphatidylinositol 3-Kinase (PI3K)/Akt Pathway
por: Xing, Feng, et al.
Publicado: (2019)

S100A16 Regulates HeLa Cell through the Phosphatidylinositol 3 Kinase (PI3K)/AKT Signaling Pathway
por: Zhang, Haibin, et al.
Publicado: (2020)

Combretastatin A4 Regulates Proliferation, Migration, Invasion, and Apoptosis of Thyroid Cancer Cells via PI3K/Akt Signaling Pathway
por: Liang, Weixin, et al.
Publicado: (2016)

Capilliposide C Sensitizes Esophageal Squamous Carcinoma Cells to Oxaliplatin by Inducing Apoptosis Through the PI3K/Akt/mTOR Pathway
por: Shen, Zhipeng, et al.
Publicado: (2017)

Diacetyl Hexamethylene Diamine (CAHB) Exerts Pro-Apoptotic and Anti-Proliferative Function in Leukemic T Lymphocytes via Downregulating PI3K/Akt Signaling
por: Hong, Ye, et al.
Publicado: (2019)

Formiminotransferase Cyclodeaminase Suppresses Hepatocellular Carcinoma by Modulating Cell Apoptosis, DNA Damage, and Phosphatidylinositol 3-Kinases (PI3K)/Akt Signaling Pathway
por: Chen, Jiajia, et al.
Publicado: (2019)

The Effects of Interleukin-33 (IL-33) on Osteosarcoma Cell Viability, Apoptosis, and Epithelial-Mesenchymal Transition are Mediated Through the PI3K/AKT Pathway
por: Wang, Shenyu, et al.
Publicado: (2020)

Piperine Inhibits Cell Proliferation and Induces Apoptosis of Human Gastric Cancer Cells by Downregulating Phosphatidylinositol 3-Kinase (PI3K)/Akt Pathway
por: Chen, Hanyu, et al.
Publicado: (2020)

The G protein-coupled estrogen receptor 1 (GPER/GPR30) does not predict survival in patients with ovarian cancer
por: Kolkova, Zuzana, et al.
Publicado: (2012)

N-Methyl Pyrrolidone (NMP) Alleviates Lipopolysaccharide (LPS)-Induced Inflammatory Injury in Articular Chondrocytes
por: Zhu, Xianping, et al.
Publicado: (2018)

Long Noncoding RNA LINC003121 Inhibits Proliferation and Invasion of Thyroid Cancer Cells by Suppression of the Phosphatidylinositol-3-Kinase (PI3K)/Akt Signaling Pathway
por: Min, Xiang, et al.
Publicado: (2018)

Osteopontin Promotes Colorectal Cancer Cell Invasion and the Stem Cell-Like Properties through the PI3K-AKT-GSK/3β-β/Catenin Pathway
por: Cheng, Yuanguang, et al.
Publicado: (2019)

Ferulic Acid Induces Apoptosis of HeLa and Caski Cervical Carcinoma Cells by Down-Regulating the Phosphatidylinositol 3-Kinase (PI3K)/Akt Signaling Pathway
por: Luo, Liping, et al.
Publicado: (2020)

Anticancer Activity of Mukonal Against Human Laryngeal Cancer Cells Involves Apoptosis, Cell Cycle Arrest, and Inhibition of PI3K/AKT and MEK/ERK Signalling Pathways
por: Li, Liu, et al.
Publicado: (2018)

Suppression of Apoptosis in Human Umbilical Vein Endothelial Cells (HUVECs) by Klotho Protein is Associated with Reduced Endoplasmic Reticulum Oxidative Stress and Activation of the PI3K/AKT Pathway
por: Cui, Wei, et al.
Publicado: (2018)

A Human Chondrocyte-Derived In Vitro Model of Alcohol-Induced and Steroid-Induced Femoral Head Necrosis
por: Qin, Xiong, et al.
Publicado: (2018)

Everolimus Reverses Palbociclib Resistance in ER+ Human Breast Cancer Cells by Inhibiting Phosphatidylinositol 3-Kinase(PI3K)/Akt/Mammalian Target of Rapamycin (mTOR) Pathway
por: Chen, Lin, et al.
Publicado: (2019)

microRNA-378a Regulates the Reactive Oxygen Species (ROS)/Phosphatidylinositol 3-Kinases (PI3K)/AKT Signaling Pathway in Human Lens Epithelial Cells and Cataract
por: Liu, Yan, et al.
Publicado: (2019)

PTEN-Induced Putative Kinase 1 (PINK1)/Parkin-Mediated Mitophagy Protects PC12 Cells Against Cisplatin-Induced Neurotoxicity
por: Zhang, Yao, et al.
Publicado: (2019)

Elevated G-Protein Receptor 125 (GPR125) Expression Predicts Good Outcomes in Colorectal Cancer and Inhibits Wnt/β-Catenin Signaling Pathway
por: Wu, Yibin, et al.
Publicado: (2018)

Anticancer Effects of Gingerol in Retinoblastoma Cancer Cells (RB355 Cell Line) Are Mediated via Apoptosis Induction, Cell Cycle Arrest and Upregulation of PI3K/Akt Signaling Pathway
por: Meng, Bo, et al.
Publicado: (2018)

Downregulation of TBC1 Domain Family Member 24 (BC1D24) Inhibits Breast Carcinoma Growth via IGF1R/PI3K/AKT Pathway
por: Qu, Xiusheng, et al.
Publicado: (2018)

Knockdown of the Sonic Hedgehog (SHH) Gene Inhibits Proliferation of Hep3B and SMMC-7721 Hepatocellular Carcinoma Cells via the PI3K/Akt/PCK1 Signaling Pathway
por: Chen, Youping, et al.
Publicado: (2019)

Inhibition of Nasopharyngeal Carcinoma by Beta-Lapachone Occurs by Targeting the Mammalian Target of Rapamycin (mTOR)/PI3K/AKT Pathway, Reactive Oxygen Species (ROS) Production, and Autophagy Induction
por: Han, Yongqing, et al.
Publicado: (2019)

Estrogen Receptor Mediates the Radiosensitivity of Triple-Negative Breast Cancer Cells
por: Chen, Xingxing, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_b0t4v4noolpqgpculal085t69b