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Elderly dendritic cells respond to LPS/IFN-γ and CD40L stimulation despite incomplete maturation
There is evidence that dendritic cells (DCs) undergo age-related changes that modulate their function with their key role being priming antigen-specific effector T cells. This occurs once DCs develop into antigen-presenting cells in response to stimuli/danger signals. However, the effects of aging o...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898732/ https://www.ncbi.nlm.nih.gov/pubmed/29652910 http://dx.doi.org/10.1371/journal.pone.0195313 |