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Protein kinase D3 modulates MMP1 and MMP13 expression in human chondrocytes

Many catabolic stimuli, including interleukin-1 (IL-1) in combination with oncostatin M (OSM), promote cartilage breakdown via the induction of collagen-degrading collagenases such as matrix metalloproteinase 1 (MMP1) and MMP13 in human articular chondrocytes. Indeed, joint diseases with an inflamma...

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Detalles Bibliográficos
Autores principales:	Baker, Jonathan, Falconer, Adrian M. D., Wilkinson, David J., Europe-Finner, G. Nicholas, Litherland, Gary J., Rowan, Andrew D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898748/ https://www.ncbi.nlm.nih.gov/pubmed/29652915 http://dx.doi.org/10.1371/journal.pone.0195864

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