Cargando…

RhoGAPp190: A potential player in tbph-mediated neurodegeneration in Drosophila

TDP-43 is an ubiquitous and highly conserved ribonucleoprotein involved in several cellular processes including pre-mRNA splicing, transcription, mRNA stability and transport. Notwithstanding the evidence of TDP-43 involvement in the pathogenesis of different neurodegenerative disorders (i.e. ALS an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Langellotti, Simona, Romano, Giulia, Feiguin, Fabian, Baralle, Francisco Ernesto, Romano, Maurizio
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898758/ https://www.ncbi.nlm.nih.gov/pubmed/29652933 http://dx.doi.org/10.1371/journal.pone.0195845

Ejemplares similares

A novel Drosophila model of TDP-43 proteinopathies: N-terminal sequences combined with the Q/N domain induce protein functional loss and locomotion defects
por: Langellotti, Simona, et al.
Publicado: (2016)

Muscleblind, BSF and TBPH are mislocalized in the muscle sarcomere of a Drosophila myotonic dystrophy model
por: Llamusi, Beatriz, et al.
Publicado: (2013)

Dissecting the splicing mechanism of the Drosophila editing enzyme; dADAR
por: Marcucci, Roberto, et al.
Publicado: (2009)

TDP-43 Regulates Drosophila Neuromuscular Junctions Growth by Modulating Futsch/MAP1B Levels and Synaptic Microtubules Organization
por: Godena, Vinay K., et al.
Publicado: (2011)

Drosophila Answers to TDP-43 Proteinopathies
por: Romano, Maurizio, et al.
Publicado: (2012)

TDP-43 prevents retrotransposon activation in the Drosophila motor system through regulation of Dicer-2 activity
por: Romano, Giulia, et al.
Publicado: (2020)

TDP-43 regulates GAD1 mRNA splicing and GABA signaling in Drosophila CNS
por: Romano, Giulia, et al.
Publicado: (2021)

Su(var)3-9 mediates age-dependent increase in H3K9 methylation on TDP-43 promoter triggering neurodegeneration
por: Marzullo, Marta, et al.
Publicado: (2023)

Glial TDP-43 regulates axon wrapping, GluRIIA clustering and fly motility by autonomous and non-autonomous mechanisms
por: Romano, Giulia, et al.
Publicado: (2015)

A novel anti-aldolase C antibody specifically interacts with residues 85–102 of the protein
por: Langellotti, Simona, et al.
Publicado: (2014)

Major hnRNP proteins act as general TDP-43 functional modifiers both in Drosophila and human neuronal cells
por: Appocher, Chiara, et al.
Publicado: (2017)

ChemGAPP: a tool for chemical genomics analysis and phenotypic profiling
por: Doherty, Hannah M, et al.
Publicado: (2023)

Rho family GTPases: key players in neuronal development, neuronal survival, and neurodegeneration
por: Stankiewicz, Trisha R., et al.
Publicado: (2014)

TDP-43 promotes the formation of neuromuscular synapses through the regulation of Disc-large expression in Drosophila skeletal muscles
por: Strah, Nina, et al.
Publicado: (2020)

Downregulation of glutamic acid decarboxylase in Drosophila TDP-43-null brains provokes paralysis by affecting the organization of the neuromuscular synapses
por: Romano, Giulia, et al.
Publicado: (2018)

p190RhoGAP is cell cycle regulated and affects cytokinesis
por: Su, Ling, et al.
Publicado: (2003)

p190RhoGAP proteins contain pseudoGTPase domains
por: Stiegler, Amy L., et al.
Publicado: (2017)

Loss of ISWI Function in Drosophila Nuclear Bodies Drives Cytoplasmic Redistribution of Drosophila TDP-43
por: Lo Piccolo, Luca, et al.
Publicado: (2018)

Mind the 'GAPP': a pre-graduation assessment of preparedness for practice amid a pandemic
por: Donnell, Christopher C., et al.
Publicado: (2022)

Associations of Dietary Intake with Urinary Melamine and Derivative Concentrations among Children in the GAPPS Cohort
por: Melough, Melissa M., et al.
Publicado: (2022)

The comprehensive review of gastric adenocarcinoma and proximal polyposis of the stomach (GAPPS) from diagnosis and treatment
por: Iwatsuki, Masaaki, et al.
Publicado: (2023)

P190B RhoGAP Regulates Chromosome Segregation in Cancer Cells
por: Hwang, Melissa, et al.
Publicado: (2012)

p190-B RhoGAP regulates the functional composition of the mesenchymal microenvironment
por: Raman, Rachna, et al.
Publicado: (2013)

Characterization of the human TARDBP gene promoter
por: Baralle, Marco, et al.
Publicado: (2021)

Haploinsufficiency for p190B RhoGAP inhibits MMTV-Neu tumor progression
por: Heckman-Stoddard, Brandy M, et al.
Publicado: (2009)

RhoA is down-regulated at cell–cell contacts via p190RhoGAP-B in response to tensional homeostasis
por: Ponik, Suzanne M., et al.
Publicado: (2013)

A Rnd3/p190RhoGAP pathway regulates RhoA activity in idiopathic pulmonary fibrosis fibroblasts
por: Monaghan-Benson, Elizabeth, et al.
Publicado: (2018)

1177. Mind the GAPP: Global Arrivals and Pre-treated Patients screening at a children’s cancer center
por: Mukkada, Sheena, et al.
Publicado: (2022)

Mechanisms of CP190 Interaction with Architectural Proteins in Drosophila Melanogaster
por: Sabirov, Marat, et al.
Publicado: (2021)

p190 RhoGAP promotes contact inhibition in epithelial cells by repressing YAP activity
por: Frank, Scott R., et al.
Publicado: (2018)

p190RhoGAPs, the ARHGAP35- and ARHGAP5-Encoded Proteins, in Health and Disease
por: Héraud, Capucine, et al.
Publicado: (2019)

Rgnef (p190RhoGEF) Knockout Inhibits RhoA Activity, Focal Adhesion Establishment, and Cell Motility Downstream of Integrins
por: Miller, Nichol L. G., et al.
Publicado: (2012)

Role of Pseudoexons and Pseudointrons in Human Cancer
por: Romano, Maurizio, et al.
Publicado: (2013)

Gabapentin for the Management of Chronic Pelvic Pain in Women (GaPP1): A Pilot Randomised Controlled Trial
por: Lewis, Steff C., et al.
Publicado: (2016)

Over-diagnosis of potential malignant behavior in MEN 2A-associated pheochromocytomas using the PASS and GAPP algorithms
por: Stenman, Adam, et al.
Publicado: (2018)

Chromatin binding of Gcn5 in Drosophila is largely mediated by CP190
por: Ali, Tamer, et al.
Publicado: (2017)

Rodent Thyroid, Liver, and Fetal Testis Toxicity of the Monoester Metabolite of Bis-(2-ethylhexyl) Tetrabromophthalate (TBPH), a Novel Brominated Flame Retardant Present in Indoor Dust
por: Springer, Cecilia, et al.
Publicado: (2012)

Rnd1 and Rnd3 targeting to lipid raft is required for p190 RhoGAP activation
por: Oinuma, Izumi, et al.
Publicado: (2012)

Correction: p190 RhoGAP promotes contact inhibition in epithelial cells by repressing YAP activity
por: Frank, Scott R., et al.
Publicado: (2018)

Complex splicing control of the human Thrombopoietin gene by intronic G runs
por: Marcucci, Roberto, et al.
Publicado: (2007)

Cannot write session to /tmp/vufind_sessions/sess_jn0074brgagmkrmd323db2av9j