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A Conserved Circadian Function for the Neurofibromatosis 1 Gene

Loss of the Neurofibromatosis 1 (Nf1) protein, neurofibromin, in Drosophila disrupts circadian rhythms of locomotor activity without impairing central clock function, suggesting effects downstream of the clock. However, the relevant cellular mechanisms are not known. Leveraging the discovery of outp...

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Detalles Bibliográficos
Autores principales: Bai, Lei, Lee, Yool, Hsu, Cynthia T., Williams, Julie A., Cavanaugh, Daniel, Zheng, Xiangzhong, Stein, Carly, Haynes, Paula, Wang, Han, Gutmann, David H., Sehgal, Amita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898822/
https://www.ncbi.nlm.nih.gov/pubmed/29590612
http://dx.doi.org/10.1016/j.celrep.2018.03.014

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