Myotubularin related protein-2 and its phospholipid substrate PIP(2) control Piezo2-mediated mechanotransduction in peripheral sensory neurons

Piezo2 ion channels are critical determinants of the sense of light touch in vertebrates. Yet, their regulation is only incompletely understood. We recently identified myotubularin related protein-2 (Mtmr2), a phosphoinositide (PI) phosphatase, in the native Piezo2 interactome of murine dorsal root...

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Detalles Bibliográficos
Autores principales: Narayanan, Pratibha, Hütte, Meike, Kudryasheva, Galina, Taberner, Francisco J, Lechner, Stefan G, Rehfeldt, Florian, Gomez-Varela, David, Schmidt, Manuela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898911/
https://www.ncbi.nlm.nih.gov/pubmed/29521261
http://dx.doi.org/10.7554/eLife.32346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898911/
https://www.ncbi.nlm.nih.gov/pubmed/29521261
http://dx.doi.org/10.7554/eLife.32346

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