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Myotubularin related protein-2 and its phospholipid substrate PIP(2) control Piezo2-mediated mechanotransduction in peripheral sensory neurons
Piezo2 ion channels are critical determinants of the sense of light touch in vertebrates. Yet, their regulation is only incompletely understood. We recently identified myotubularin related protein-2 (Mtmr2), a phosphoinositide (PI) phosphatase, in the native Piezo2 interactome of murine dorsal root...
Autores principales: | Narayanan, Pratibha, Hütte, Meike, Kudryasheva, Galina, Taberner, Francisco J, Lechner, Stefan G, Rehfeldt, Florian, Gomez-Varela, David, Schmidt, Manuela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
eLife Sciences Publications, Ltd
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898911/ https://www.ncbi.nlm.nih.gov/pubmed/29521261 http://dx.doi.org/10.7554/eLife.32346 |
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