Cargando…

Neurovascular sequestration in paediatric P. falciparum malaria is visible clinically in the retina

Retinal vessel changes and retinal whitening, distinctive features of malarial retinopathy, can be directly observed during routine eye examination in children with P. falciparum cerebral malaria. We investigated their clinical significance and underlying mechanisms through linked clinical, clinicop...

Descripción completa

Detalles Bibliográficos
Autores principales:	Barrera, Valentina, MacCormick, Ian James Callum, Czanner, Gabriela, Hiscott, Paul Stephenson, White, Valerie Ann, Craig, Alister Gordon, Beare, Nicholas Alexander Venton, Culshaw, Lucy Hazel, Zheng, Yalin, Biddolph, Simon Charles, Milner, Danny Arnold, Kamiza, Steve, Molyneux, Malcolm Edward, Taylor, Terrie Ellen, Harding, Simon Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2018
Materias:	Human Biology and Medicine
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5898913/ https://www.ncbi.nlm.nih.gov/pubmed/29578406 http://dx.doi.org/10.7554/eLife.32208

Ejemplares similares

Severity of Retinopathy Parallels the Degree of Parasite Sequestration in the Eyes and Brains of Malawian Children With Fatal Cerebral Malaria
por: Barrera, Valentina, et al.
Publicado: (2015)

Cerebral malaria in children: using the retina to study the brain
por: MacCormick, Ian J. C., et al.
Publicado: (2014)

Spatial statistical modelling of capillary non-perfusion in the retina
por: MacCormick, Ian J. C., et al.
Publicado: (2017)

How Does Blood-Retinal Barrier Breakdown Relate to Death and Disability in Pediatric Cerebral Malaria?
por: MacCormick, Ian J C, et al.
Publicado: (2020)

Reply: Retinopathy, histidine-rich protein-2 and perfusion pressure in cerebral malaria
por: MacCormick, Ian J. C., et al.
Publicado: (2014)

Correlation of hemorrhage, axonal damage, and blood-tissue barrier disruption in brain and retina of Malawian children with fatal cerebral malaria
por: Greiner, Jesse, et al.
Publicado: (2015)

A Comprehensive Texture Segmentation Framework for Segmentation of Capillary Non-Perfusion Regions in Fundus Fluorescein Angiograms
por: Zheng, Yalin, et al.
Publicado: (2014)

Automated Detection of Vessel Abnormalities on Fluorescein Angiogram in Malarial Retinopathy
por: Zhao, Yitian, et al.
Publicado: (2015)

Longitudinal Visuomotor Development in a Malaria Endemic Area: Cerebral Malaria and Beyond
por: Knox, Paul C., et al.
Publicado: (2016)

Automated Detection of Leakage in Fluorescein Angiography Images with Application to Malarial Retinopathy
por: Zhao, Yitian, et al.
Publicado: (2015)

Developing retinal biomarkers of neurological disease: an analytical perspective
por: MacCormick, Ian JC, et al.
Publicado: (2015)

Spatial and spatio-temporal statistical analyses of retinal images: a review of methods and applications
por: Zhu, Wenyue, et al.
Publicado: (2020)

Grading fluorescein angiograms in malarial retinopathy
por: MacCormick, Ian J. C., et al.
Publicado: (2015)

Automated Detection of Malarial Retinopathy in Digital Fundus Images for Improved Diagnosis in Malawian Children with Clinically Defined Cerebral Malaria
por: Joshi, Vinayak, et al.
Publicado: (2017)

The Neuropathology of Fatal Cerebral Malaria in Malawian Children
por: Dorovini-Zis, Katerina, et al.
Publicado: (2011)

Early alterations of neurovascular unit in the retina in mouse models of tauopathy
por: Xia, Fan, et al.
Publicado: (2021)

Malarial retinopathy affecting visual function in a Malawian adult with cerebral malaria
por: Piddock, Katherine, et al.
Publicado: (2014)

Accurate, fast, data efficient and interpretable glaucoma diagnosis with automated spatial analysis of the whole cup to disc profile
por: MacCormick, Ian J. C., et al.
Publicado: (2019)

Correction: Accurate, fast, data efficient and interpretable glaucoma diagnosis with automated spatial analysis of the whole cup to disc profile
por: MacCormick, Ian J. C., et al.
Publicado: (2019)

The systemic pathology of cerebral malaria in African children
por: Milner, Danny A., et al.
Publicado: (2014)

Evidence from a natural experiment that malaria parasitemia is pathogenic in retinopathy-negative cerebral malaria
por: Small, Dylan S, et al.
Publicado: (2017)

Lisosan G Protects the Retina from Neurovascular Damage in Experimental Diabetic Retinopathy
por: Amato, Rosario, et al.
Publicado: (2018)

Sufficient Cav-1 levels in the endothelium are critical for the maintenance of the neurovascular unit in the retina
por: Wang, Yixin, et al.
Publicado: (2023)

Epidemiology of diabetic retinopathy and maculopathy in Africa: a systematic review
por: Burgess, P I, et al.
Publicado: (2013)

Comparison of CD8(+) T Cell Accumulation in the Brain During Human and Murine Cerebral Malaria
por: Barrera, Valentina, et al.
Publicado: (2019)

Non-invasive evaluation of neurovascular coupling in the murine retina by dynamic retinal vessel analysis
por: Albanna, Walid, et al.
Publicado: (2018)

Hypoxic–ischemic injury causes functional and structural neurovascular degeneration in the juvenile mouse retina
por: Zaitoun, Ismail S., et al.
Publicado: (2021)

Early neurovascular changes in the retina in preclinical diabetic retinopathy and its relation with blood glucose
por: Li, Hui, et al.
Publicado: (2021)

Evidence for spleen dysfunction in malaria-HIV co-infection in a subset of pediatric patients
por: Joice, Regina, et al.
Publicado: (2016)

Safety of lumbar puncture in comatose children with clinical features of cerebral malaria
por: Moxon, Christopher A., et al.
Publicado: (2016)

Cerebral malaria—using the retina to study the brain
por: Beare, Nicholas A. V.
Publicado: (2023)

Visual risk factors for falls in older adults: a case-control study
por: Mehta, Jignasa, et al.
Publicado: (2022)

Transcriptional profiling defines dynamics of parasite tissue sequestration during malaria infection
por: Pelle, Karell G, et al.
Publicado: (2015)

Severe Neurovascular Compromise Associated with Plastic Deformation of Ulna Elastic Nail Following Forearm Re-fracture
por: Borton, Zakk M, et al.
Publicado: (2019)

A histological method for quantifying Plasmodium falciparum in the brain in fatal paediatric cerebral malaria
por: Milner, Danny A, et al.
Publicado: (2013)

Early Microvascular and Oscillatory Potentials Changes in Human Diabetic Retina: Amacrine Cells and the Intraretinal Neurovascular Crosstalk
por: Midena, Edoardo, et al.
Publicado: (2021)

Retinal Pathology of Pediatric Cerebral Malaria in Malawi
por: White, Valerie A., et al.
Publicado: (2009)

Adult bacterial conjunctivitis: resistance patterns over 12 years in patients attending a large primary eye care centre in the UK
por: Silvester, Alexander, et al.
Publicado: (2016)

Advances in cell therapies using stem cells/progenitors as a novel approach for neurovascular repair of the diabetic retina
por: Lechner, Judith, et al.
Publicado: (2022)

Metabolism in the Zebrafish Retina
por: Jaroszynska, Natalia, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_b0khr5086gp3algk3ig1fkm1f6