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Deciphering the mechanism of action of 089, a compound impairing the fungal cell cycle

Fungal infections represent an increasingly relevant clinical problem, primarily because of the increased survival of severely immune-compromised patients. Despite the availability of active and selective drugs and of well-established prophylaxis, classical antifungals are often ineffective as resis...

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Detalles Bibliográficos
Autores principales: Stefanini, Irene, Rizzetto, Lisa, Rivero, Damariz, Carbonell, Silvia, Gut, Marta, Heath, Simon, Gut, Ivo G., Trabocchi, Andrea, Guarna, Antonio, Ben Ghazzi, Nagwa, Bowyer, Paul, Kapushesky, Misha, Cavalieri, Duccio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899093/
https://www.ncbi.nlm.nih.gov/pubmed/29654251
http://dx.doi.org/10.1038/s41598-018-24341-y