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Cell-free prediction of protein expression costs for growing cells
Translating heterologous proteins places significant burden on host cells, consuming expression resources leading to slower cell growth and productivity. Yet predicting the cost of protein production for any given gene is a major challenge, as multiple processes and factors combine to determine tran...
Autores principales: | Borkowski, Olivier, Bricio, Carlos, Murgiano, Michela, Rothschild-Mancinelli, Brooke, Stan, Guy-Bart, Ellis, Tom |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899134/ https://www.ncbi.nlm.nih.gov/pubmed/29654285 http://dx.doi.org/10.1038/s41467-018-03970-x |
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