A TAD boundary is preserved upon deletion of the CTCF-rich Firre locus

The binding of the transcriptional regulator CTCF to the genome has been implicated in the formation of topologically associated domains (TADs). However, the general mechanisms of folding the genome into TADs are not fully understood. Here we test the effects of deleting a CTCF-rich locus on TAD bou...

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Detalles Bibliográficos
Autores principales: Barutcu, A. Rasim, Maass, Philipp G., Lewandowski, Jordan P., Weiner, Catherine L., Rinn, John L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899154/
https://www.ncbi.nlm.nih.gov/pubmed/29654311
http://dx.doi.org/10.1038/s41467-018-03614-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899154/
https://www.ncbi.nlm.nih.gov/pubmed/29654311
http://dx.doi.org/10.1038/s41467-018-03614-0

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