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A fast and cost-effective method for apolipoprotein E isotyping as an alternative to APOE genotyping for patient screening and stratification

Apolipoprotein E (apoE) is a 34 kDa glycoprotein involved in lipid metabolism. The human APOE gene encodes for three different apoE protein isoforms: E2, E3 and E4. The interest in apoE isoforms is high for epidemiological research, patient stratification and identification of those at increased ris...

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Detalles Bibliográficos
Autores principales: Calero, Olga, García-Albert, Luis, Rodríguez-Martín, Andrés, Veiga, Sergio, Calero, Miguel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899170/
https://www.ncbi.nlm.nih.gov/pubmed/29654261
http://dx.doi.org/10.1038/s41598-018-24320-3