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Naturally Occurring Mutations in HIV-1 CRF01_AE Capsid Affect Viral Sensitivity to Restriction Factors

TRIM5α and MxB are known as restriction factors that inhibit the early step of intracellular HIV-1 replication cycle. Both factors are believed to interact with the incoming virus core to suppress HIV-1 infection. The extreme diversity of HIV-1 is thought to be a consequence of its propensity to mut...

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Detalles Bibliográficos
Autores principales: Nakayama, Emi E., Saito, Akatsuki, Sultana, Tahmina, Jin, Zhuan, Nohata, Kyotaro, Shibata, Masato, Hosoi, Miho, Motomura, Kazushi, Shioda, Tatsuo, Sangkitporn, Somchai, Loket, Ruangchai, Saeng-aroon, Siriphan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Mary Ann Liebert, Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899301/
https://www.ncbi.nlm.nih.gov/pubmed/29325426
http://dx.doi.org/10.1089/aid.2017.0212