Phosphorylated TDP-43 (pTDP-43) aggregates in the axial skeletal muscle of patients with sporadic and familial amyotrophic lateral sclerosis

Muscle atrophy with weakness is a core feature of amyotrophic lateral sclerosis (ALS) that has long been attributed to motor neuron loss alone. However, several studies in ALS patients, and more so in animal models, have challenged this assumption with the latter providing direct evidence that muscl...

Descripción completa

Detalles Bibliográficos
Autores principales: Cykowski, Matthew D., Powell, Suzanne Z., Appel, Joan W., Arumanayagam, Anithachristy S., Rivera, Andreana L., Appel, Stanley H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899326/
https://www.ncbi.nlm.nih.gov/pubmed/29653597
http://dx.doi.org/10.1186/s40478-018-0528-y

Ejemplares similares

Ejemplares similares