Rlip depletion prevents spontaneous neoplasia in TP53 null mice

TP53 (p53) is a tumor suppressor whose functions are lost or altered in most malignancies. p53 homozygous knockout (p53(−/−)) mice uniformly die of spontaneous malignancy, typically T-cell lymphoma. RALBP1 (RLIP76, Rlip) is a stress-protective, mercapturic acid pathway transporter protein that also...

Descripción completa

Detalles Bibliográficos
Autores principales: Awasthi, Sanjay, Tompkins, Joshua, Singhal, Jyotsana, Riggs, Arthur D., Yadav, Sushma, Wu, Xiwei, Singh, Sharda, Warden, Charles, Liu, Zheng, Wang, Jinhui, Slavin, Thomas P., Weitzel, Jeffrey N., Yuan, Yate-Ching, Awasthi, Meenakshi, Srivastava, Satish K., Awasthi, Yogesh C., Singhal, Sharad S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Biological Sciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899455/
https://www.ncbi.nlm.nih.gov/pubmed/29572430
http://dx.doi.org/10.1073/pnas.1719586115

Ejemplares similares

Ejemplares similares