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Crystal structure of human lysyl oxidase-like 2 (hLOXL2) in a precursor state

Lysyl oxidases (LOXs), a type of copper- and lysyl tyrosylquinone (LTQ) -dependent amine oxidase, catalyze the oxidative deamination of lysine residues of extracellular matrix (ECM) proteins such as elastins and collagens and generate aldehyde groups. The oxidative deamination of lysine represents t...

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Detalles Bibliográficos
Autores principales: Zhang, Xi, Wang, Qifan, Wu, Jianping, Wang, Jiawei, Shi, Yigong, Liu, Minhao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: National Academy of Sciences 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899467/
https://www.ncbi.nlm.nih.gov/pubmed/29581294
http://dx.doi.org/10.1073/pnas.1720859115