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Crystal structure of human lysyl oxidase-like 2 (hLOXL2) in a precursor state
Lysyl oxidases (LOXs), a type of copper- and lysyl tyrosylquinone (LTQ) -dependent amine oxidase, catalyze the oxidative deamination of lysine residues of extracellular matrix (ECM) proteins such as elastins and collagens and generate aldehyde groups. The oxidative deamination of lysine represents t...
Autores principales: | Zhang, Xi, Wang, Qifan, Wu, Jianping, Wang, Jiawei, Shi, Yigong, Liu, Minhao |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
National Academy of Sciences
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899467/ https://www.ncbi.nlm.nih.gov/pubmed/29581294 http://dx.doi.org/10.1073/pnas.1720859115 |
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