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Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection

Background: Preoperative coronary angiography is often not performed in acute Type A dissection. We examined differences in the incidence of pre-existing coronary disease and subsequent coronary events between patients undergoing acute Type A dissection repair and patients undergoing elective proxim...

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Autores principales: Tang, Paul C., Akhter, Shahab A., Osaki, Satoru, Lozonschi, Lucian, Kohmoto, Takushi, De Oliveira, Nilto C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical Publishers 2017
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899605/
https://www.ncbi.nlm.nih.gov/pubmed/29675439
http://dx.doi.org/10.12945/j.aorta.2017.16.058
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author Tang, Paul C.
Akhter, Shahab A.
Osaki, Satoru
Lozonschi, Lucian
Kohmoto, Takushi
De Oliveira, Nilto C.
author_facet Tang, Paul C.
Akhter, Shahab A.
Osaki, Satoru
Lozonschi, Lucian
Kohmoto, Takushi
De Oliveira, Nilto C.
author_sort Tang, Paul C.
collection PubMed
description Background: Preoperative coronary angiography is often not performed in acute Type A dissection. We examined differences in the incidence of pre-existing coronary disease and subsequent coronary events between patients undergoing acute Type A dissection repair and patients undergoing elective proximal aortic aneurysm repair. Methods: From 2000 to 2015, there were 154 acute Type A dissection repairs and 457 elective proximal aortic aneurysm repairs. We performed a retrospective review to evaluate preoperative coronary disease and postoperative coronary interventions such as percutaneous coronary intervention (PCI) and coronary bypass grafting (CABG). Results: A total of 31 (20%) dissection patients and 123 (27%) elective surgery patients had preoperative evidence of coronary artery disease (p = 0.094). All elective surgery patients but only six (4%) dissection patients had preoperative coronary catheterization. More CABGs were performed in the elective surgery group (19%) than in the dissection group (3%, p < 0.001). There were no differences in the incidence of prior PCI, CABG, or myocardial infarction between groups. Following dissection repair, four patients required coronary interventions. Of these, two (1.3%) experienced chest pain and underwent PCI at 4.7 and 4.3 months postoperatively, respectively, and another two experienced symptoms and required PCI at 5 and 7 years, respectively. The 30-day and 14-year mortality rates after dissection repair were 13% and 24%, respectively. Although the dissection group had poorer survival than the elective surgery group (p < 0.001), there was no difference in conditional survival after aortic-related deaths over the first year were censored (p = 0.104). Conclusions: Given the low incidence of missed significant coronary disease (1.3%), it is reasonable to perform Type A dissection repair without coronary angiography.
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spelling pubmed-58996052018-04-19 Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection Tang, Paul C. Akhter, Shahab A. Osaki, Satoru Lozonschi, Lucian Kohmoto, Takushi De Oliveira, Nilto C. Aorta (Stamford) Background: Preoperative coronary angiography is often not performed in acute Type A dissection. We examined differences in the incidence of pre-existing coronary disease and subsequent coronary events between patients undergoing acute Type A dissection repair and patients undergoing elective proximal aortic aneurysm repair. Methods: From 2000 to 2015, there were 154 acute Type A dissection repairs and 457 elective proximal aortic aneurysm repairs. We performed a retrospective review to evaluate preoperative coronary disease and postoperative coronary interventions such as percutaneous coronary intervention (PCI) and coronary bypass grafting (CABG). Results: A total of 31 (20%) dissection patients and 123 (27%) elective surgery patients had preoperative evidence of coronary artery disease (p = 0.094). All elective surgery patients but only six (4%) dissection patients had preoperative coronary catheterization. More CABGs were performed in the elective surgery group (19%) than in the dissection group (3%, p < 0.001). There were no differences in the incidence of prior PCI, CABG, or myocardial infarction between groups. Following dissection repair, four patients required coronary interventions. Of these, two (1.3%) experienced chest pain and underwent PCI at 4.7 and 4.3 months postoperatively, respectively, and another two experienced symptoms and required PCI at 5 and 7 years, respectively. The 30-day and 14-year mortality rates after dissection repair were 13% and 24%, respectively. Although the dissection group had poorer survival than the elective surgery group (p < 0.001), there was no difference in conditional survival after aortic-related deaths over the first year were censored (p = 0.104). Conclusions: Given the low incidence of missed significant coronary disease (1.3%), it is reasonable to perform Type A dissection repair without coronary angiography. Thieme Medical Publishers 2017-06 2018-09-24 /pmc/articles/PMC5899605/ /pubmed/29675439 http://dx.doi.org/10.12945/j.aorta.2017.16.058 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Tang, Paul C.
Akhter, Shahab A.
Osaki, Satoru
Lozonschi, Lucian
Kohmoto, Takushi
De Oliveira, Nilto C.
Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection
title Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection
title_full Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection
title_fullStr Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection
title_full_unstemmed Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection
title_short Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection
title_sort coronary events in patients presenting for repair of acute type a aortic dissection
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899605/
https://www.ncbi.nlm.nih.gov/pubmed/29675439
http://dx.doi.org/10.12945/j.aorta.2017.16.058
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