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Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection
Background: Preoperative coronary angiography is often not performed in acute Type A dissection. We examined differences in the incidence of pre-existing coronary disease and subsequent coronary events between patients undergoing acute Type A dissection repair and patients undergoing elective proxim...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Thieme Medical Publishers
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899605/ https://www.ncbi.nlm.nih.gov/pubmed/29675439 http://dx.doi.org/10.12945/j.aorta.2017.16.058 |
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author | Tang, Paul C. Akhter, Shahab A. Osaki, Satoru Lozonschi, Lucian Kohmoto, Takushi De Oliveira, Nilto C. |
author_facet | Tang, Paul C. Akhter, Shahab A. Osaki, Satoru Lozonschi, Lucian Kohmoto, Takushi De Oliveira, Nilto C. |
author_sort | Tang, Paul C. |
collection | PubMed |
description | Background: Preoperative coronary angiography is often not performed in acute Type A dissection. We examined differences in the incidence of pre-existing coronary disease and subsequent coronary events between patients undergoing acute Type A dissection repair and patients undergoing elective proximal aortic aneurysm repair. Methods: From 2000 to 2015, there were 154 acute Type A dissection repairs and 457 elective proximal aortic aneurysm repairs. We performed a retrospective review to evaluate preoperative coronary disease and postoperative coronary interventions such as percutaneous coronary intervention (PCI) and coronary bypass grafting (CABG). Results: A total of 31 (20%) dissection patients and 123 (27%) elective surgery patients had preoperative evidence of coronary artery disease (p = 0.094). All elective surgery patients but only six (4%) dissection patients had preoperative coronary catheterization. More CABGs were performed in the elective surgery group (19%) than in the dissection group (3%, p < 0.001). There were no differences in the incidence of prior PCI, CABG, or myocardial infarction between groups. Following dissection repair, four patients required coronary interventions. Of these, two (1.3%) experienced chest pain and underwent PCI at 4.7 and 4.3 months postoperatively, respectively, and another two experienced symptoms and required PCI at 5 and 7 years, respectively. The 30-day and 14-year mortality rates after dissection repair were 13% and 24%, respectively. Although the dissection group had poorer survival than the elective surgery group (p < 0.001), there was no difference in conditional survival after aortic-related deaths over the first year were censored (p = 0.104). Conclusions: Given the low incidence of missed significant coronary disease (1.3%), it is reasonable to perform Type A dissection repair without coronary angiography. |
format | Online Article Text |
id | pubmed-5899605 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | Thieme Medical Publishers |
record_format | MEDLINE/PubMed |
spelling | pubmed-58996052018-04-19 Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection Tang, Paul C. Akhter, Shahab A. Osaki, Satoru Lozonschi, Lucian Kohmoto, Takushi De Oliveira, Nilto C. Aorta (Stamford) Background: Preoperative coronary angiography is often not performed in acute Type A dissection. We examined differences in the incidence of pre-existing coronary disease and subsequent coronary events between patients undergoing acute Type A dissection repair and patients undergoing elective proximal aortic aneurysm repair. Methods: From 2000 to 2015, there were 154 acute Type A dissection repairs and 457 elective proximal aortic aneurysm repairs. We performed a retrospective review to evaluate preoperative coronary disease and postoperative coronary interventions such as percutaneous coronary intervention (PCI) and coronary bypass grafting (CABG). Results: A total of 31 (20%) dissection patients and 123 (27%) elective surgery patients had preoperative evidence of coronary artery disease (p = 0.094). All elective surgery patients but only six (4%) dissection patients had preoperative coronary catheterization. More CABGs were performed in the elective surgery group (19%) than in the dissection group (3%, p < 0.001). There were no differences in the incidence of prior PCI, CABG, or myocardial infarction between groups. Following dissection repair, four patients required coronary interventions. Of these, two (1.3%) experienced chest pain and underwent PCI at 4.7 and 4.3 months postoperatively, respectively, and another two experienced symptoms and required PCI at 5 and 7 years, respectively. The 30-day and 14-year mortality rates after dissection repair were 13% and 24%, respectively. Although the dissection group had poorer survival than the elective surgery group (p < 0.001), there was no difference in conditional survival after aortic-related deaths over the first year were censored (p = 0.104). Conclusions: Given the low incidence of missed significant coronary disease (1.3%), it is reasonable to perform Type A dissection repair without coronary angiography. Thieme Medical Publishers 2017-06 2018-09-24 /pmc/articles/PMC5899605/ /pubmed/29675439 http://dx.doi.org/10.12945/j.aorta.2017.16.058 Text en https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Tang, Paul C. Akhter, Shahab A. Osaki, Satoru Lozonschi, Lucian Kohmoto, Takushi De Oliveira, Nilto C. Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection |
title | Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection |
title_full | Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection |
title_fullStr | Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection |
title_full_unstemmed | Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection |
title_short | Coronary Events in Patients Presenting for Repair of Acute Type A Aortic Dissection |
title_sort | coronary events in patients presenting for repair of acute type a aortic dissection |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899605/ https://www.ncbi.nlm.nih.gov/pubmed/29675439 http://dx.doi.org/10.12945/j.aorta.2017.16.058 |
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