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Population pharmacokinetics/pharmacodynamics of micafungin against Candida species in obese, critically ill, and morbidly obese critically ill patients

BACKGROUND: Dosing in obese critically ill patients is challenging due to pathophysiological changes derived from obesity and/or critical illness, and it remains fully unexplored. This study estimated the micafungin probability of reaching adequate 24-h area under the curve (AUC(0–24h))/minimum inhi...

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Detalles Bibliográficos
Autores principales:	Maseda, Emilio, Grau, Santiago, Luque, Sonia, Castillo-Mafla, Maria-Pilar, Suárez-de-la-Rica, Alejandro, Montero-Feijoo, Ana, Salgado, Patricia, Gimenez, Maria-Jose, García-Bernedo, Carlos A., Gilsanz, Fernando, Roberts, Jason A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2018
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899833/ https://www.ncbi.nlm.nih.gov/pubmed/29655372 http://dx.doi.org/10.1186/s13054-018-2019-8

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