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Treatment and Pathology of an Unusual Large Carcinoma of the Conjunctiva
Carcinoma of the conjunctiva is a malignant tumor which is mostly detected and surgically treated at an early stage because of medical or cosmetic problems. Exceptions of this rule may occur in developing countries, where patients do not have access to standard medical care systems. We report the ca...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899844/ https://www.ncbi.nlm.nih.gov/pubmed/29805827 http://dx.doi.org/10.1155/2018/8461737 |
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author | Stahnke, Thomas Kilangalanga, Ngoy Knappe, Steffi Guthoff, Rudolf F. Erbersdobler, Andreas |
author_facet | Stahnke, Thomas Kilangalanga, Ngoy Knappe, Steffi Guthoff, Rudolf F. Erbersdobler, Andreas |
author_sort | Stahnke, Thomas |
collection | PubMed |
description | Carcinoma of the conjunctiva is a malignant tumor which is mostly detected and surgically treated at an early stage because of medical or cosmetic problems. Exceptions of this rule may occur in developing countries, where patients do not have access to standard medical care systems. We report the case of a conjunctival carcinoma in an African patient with an unusually late presentation. Because of local medical shortcomings, and considering the severe, transmural inflammation of anterior ocular structures, an exenteration was performed although the orbit was not deeply involved with the tumor. The strong nuclear expression of p53 indicates a major role of UV exposure in this case. A total of 16-month follow-up in this patient and larger published series suggest that the risk of metastasis is rather low under those circumstances, even with invasive tumors. |
format | Online Article Text |
id | pubmed-5899844 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-58998442018-05-27 Treatment and Pathology of an Unusual Large Carcinoma of the Conjunctiva Stahnke, Thomas Kilangalanga, Ngoy Knappe, Steffi Guthoff, Rudolf F. Erbersdobler, Andreas Case Rep Ophthalmol Med Case Report Carcinoma of the conjunctiva is a malignant tumor which is mostly detected and surgically treated at an early stage because of medical or cosmetic problems. Exceptions of this rule may occur in developing countries, where patients do not have access to standard medical care systems. We report the case of a conjunctival carcinoma in an African patient with an unusually late presentation. Because of local medical shortcomings, and considering the severe, transmural inflammation of anterior ocular structures, an exenteration was performed although the orbit was not deeply involved with the tumor. The strong nuclear expression of p53 indicates a major role of UV exposure in this case. A total of 16-month follow-up in this patient and larger published series suggest that the risk of metastasis is rather low under those circumstances, even with invasive tumors. Hindawi 2018-04-01 /pmc/articles/PMC5899844/ /pubmed/29805827 http://dx.doi.org/10.1155/2018/8461737 Text en Copyright © 2018 Thomas Stahnke et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Case Report Stahnke, Thomas Kilangalanga, Ngoy Knappe, Steffi Guthoff, Rudolf F. Erbersdobler, Andreas Treatment and Pathology of an Unusual Large Carcinoma of the Conjunctiva |
title | Treatment and Pathology of an Unusual Large Carcinoma of the Conjunctiva |
title_full | Treatment and Pathology of an Unusual Large Carcinoma of the Conjunctiva |
title_fullStr | Treatment and Pathology of an Unusual Large Carcinoma of the Conjunctiva |
title_full_unstemmed | Treatment and Pathology of an Unusual Large Carcinoma of the Conjunctiva |
title_short | Treatment and Pathology of an Unusual Large Carcinoma of the Conjunctiva |
title_sort | treatment and pathology of an unusual large carcinoma of the conjunctiva |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899844/ https://www.ncbi.nlm.nih.gov/pubmed/29805827 http://dx.doi.org/10.1155/2018/8461737 |
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