Granuloma Annulare in the Setting of Secukinumab

Granuloma annulare (GA) is a common benign inflammatory skin condition classically presenting as skin-colored to erythematous dermal papules and annular plaques. Histologically, GA displays a dermal granulomatous infiltrate with palisaded histiocytes surrounding focally altered collagen. The exactly...

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Autores principales: Clark, Matthew L., Tobin, Courtney A., Sutton, Angela, Missall, Tricia Ann
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899846/
https://www.ncbi.nlm.nih.gov/pubmed/29805815
http://dx.doi.org/10.1155/2018/5175319
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author Clark, Matthew L.
Tobin, Courtney A.
Sutton, Angela
Missall, Tricia Ann
author_facet Clark, Matthew L.
Tobin, Courtney A.
Sutton, Angela
Missall, Tricia Ann
author_sort Clark, Matthew L.
collection PubMed
description Granuloma annulare (GA) is a common benign inflammatory skin condition classically presenting as skin-colored to erythematous dermal papules and annular plaques. Histologically, GA displays a dermal granulomatous infiltrate with palisaded histiocytes surrounding focally altered collagen. The exactly etiology of GA remains unknown, but it has been associated with trauma, various infections, diabetes mellitus, malignancy, thyroid disease, dyslipidemia, and several medications. In 2017, a case of GA developing in a patient treated with the interleukin 17A antagonist secukinumab was reported. Here we report a second case of GA in association with secukinumab use.
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spelling pubmed-58998462018-05-27 Granuloma Annulare in the Setting of Secukinumab Clark, Matthew L. Tobin, Courtney A. Sutton, Angela Missall, Tricia Ann Case Rep Dermatol Med Case Report Granuloma annulare (GA) is a common benign inflammatory skin condition classically presenting as skin-colored to erythematous dermal papules and annular plaques. Histologically, GA displays a dermal granulomatous infiltrate with palisaded histiocytes surrounding focally altered collagen. The exactly etiology of GA remains unknown, but it has been associated with trauma, various infections, diabetes mellitus, malignancy, thyroid disease, dyslipidemia, and several medications. In 2017, a case of GA developing in a patient treated with the interleukin 17A antagonist secukinumab was reported. Here we report a second case of GA in association with secukinumab use. Hindawi 2018-04-01 /pmc/articles/PMC5899846/ /pubmed/29805815 http://dx.doi.org/10.1155/2018/5175319 Text en Copyright © 2018 Matthew L. Clark et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Clark, Matthew L.
Tobin, Courtney A.
Sutton, Angela
Missall, Tricia Ann
Granuloma Annulare in the Setting of Secukinumab
title Granuloma Annulare in the Setting of Secukinumab
title_full Granuloma Annulare in the Setting of Secukinumab
title_fullStr Granuloma Annulare in the Setting of Secukinumab
title_full_unstemmed Granuloma Annulare in the Setting of Secukinumab
title_short Granuloma Annulare in the Setting of Secukinumab
title_sort granuloma annulare in the setting of secukinumab
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899846/
https://www.ncbi.nlm.nih.gov/pubmed/29805815
http://dx.doi.org/10.1155/2018/5175319
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AT tobincourtneya granulomaannulareinthesettingofsecukinumab
AT suttonangela granulomaannulareinthesettingofsecukinumab
AT missalltriciaann granulomaannulareinthesettingofsecukinumab

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