Cargando…

Axonal abnormalities in vanishing white matter

OBJECTIVE: We aimed to study the occurrence and development of axonal pathology and the influence of astrocytes in vanishing white matter. METHODS: Axons and myelin were analyzed using electron microscopy and immunohistochemistry on Eif2b4 and Eif2b5 single‐ and double‐mutant mice and patient brain...

Descripción completa

Detalles Bibliográficos
Autores principales: Klok, Melanie D., Bugiani, Marianna, de Vries, Sharon I., Gerritsen, Wouter, Breur, Marjolein, van der Sluis, Sophie, Heine, Vivi M., Kole, Maarten H. P., Baron, Wia, van der Knaap, Marjo S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899913/
https://www.ncbi.nlm.nih.gov/pubmed/29687020
http://dx.doi.org/10.1002/acn3.540