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Axonal abnormalities in vanishing white matter
OBJECTIVE: We aimed to study the occurrence and development of axonal pathology and the influence of astrocytes in vanishing white matter. METHODS: Axons and myelin were analyzed using electron microscopy and immunohistochemistry on Eif2b4 and Eif2b5 single‐ and double‐mutant mice and patient brain...
Autores principales: | Klok, Melanie D., Bugiani, Marianna, de Vries, Sharon I., Gerritsen, Wouter, Breur, Marjolein, van der Sluis, Sophie, Heine, Vivi M., Kole, Maarten H. P., Baron, Wia, van der Knaap, Marjo S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5899913/ https://www.ncbi.nlm.nih.gov/pubmed/29687020 http://dx.doi.org/10.1002/acn3.540 |
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