Cargando…

Targeting Cytosolic Nucleic Acid-Sensing Pathways for Cancer Immunotherapies

The innate immune system provides the first line of defense against pathogen infection though also influences pathways involved in cancer immunosurveillance. The innate immune system relies on a limited set of germ line-encoded sensors termed pattern recognition receptors (PRRs), signaling proteins...

Descripción completa

Detalles Bibliográficos
Autores principales:	Iurescia, Sandra, Fioretti, Daniela, Rinaldi, Monica
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900005/ https://www.ncbi.nlm.nih.gov/pubmed/29686682 http://dx.doi.org/10.3389/fimmu.2018.00711

Ejemplares similares

Post-Translational Modifications of Proteins in Cytosolic Nucleic Acid Sensing Signaling Pathways
por: Deng, Yu, et al.
Publicado: (2022)

The Innate Immune Signalling Pathways: Turning RIG-I Sensor Activation against Cancer
por: Iurescia, Sandra, et al.
Publicado: (2020)

DNA Vaccines: Developing New Strategies against Cancer
por: Fioretti, Daniela, et al.
Publicado: (2010)

Cellular Metabolites Regulate Central Nucleic Acid Sensing Pathways
por: Blay-Cadanet, Julia, et al.
Publicado: (2021)

Development of Spherical Nucleic Acids for Prostate Cancer Immunotherapy
por: Qin, Lei, et al.
Publicado: (2020)

The Role of Nucleases and Nucleic Acid Editing Enzymes in the Regulation of Self-Nucleic Acid Sensing
por: Santa, Pauline, et al.
Publicado: (2021)

Sensing Microbial RNA in the Cytosol
por: Vabret, Nicolas, et al.
Publicado: (2013)

Corrigendum: The Role of Nucleases and Nucleic Acid Editing Enzymes in the Regulation of Self-Nucleic Acid Sensing
por: Santa, Pauline, et al.
Publicado: (2021)

BTK: sensing pathogenic nucleic acids
por: Lee, Koon-Guan, et al.
Publicado: (2015)

Protein Dynamics in Cytosolic DNA-Sensing Antiviral Innate Immune Signaling Pathways
por: Zheng, Chunfu
Publicado: (2020)

Human Cancer Cells Sense Cytosolic Nucleic Acids Through the RIG-I–MAVS Pathway and cGAS–STING Pathway
por: Qiao, Yuan, et al.
Publicado: (2021)

Nucleic Acid Sensing by Toll-Like Receptors in the Endosomal Compartment
por: Miyake, Kensuke, et al.
Publicado: (2022)

OAS proteins and cGAS: unifying concepts in sensing and responding to cytosolic nucleic acids
por: Hornung, Veit, et al.
Publicado: (2014)

Vaccinia Virus Activation and Antagonism of Cytosolic DNA Sensing
por: El-Jesr, Misbah, et al.
Publicado: (2020)

Self-Nucleic Acid Sensing: A Novel Crucial Pathway Involved in Obesity-Mediated Metaflammation and Metabolic Syndrome
por: Ferriere, Amandine, et al.
Publicado: (2021)

Nucleic Acid Sensing Pathways in DNA Repair Targeted Cancer Therapy
por: Xie, Bingteng, et al.
Publicado: (2022)

RETRACTED ARTICLE: Nucleic acid sensing activates the innate cytosolic surveillance pathway and promotes parasite survival in visceral leishmaniasis
por: Das, Sushmita, et al.
Publicado: (2019)

Retraction Note: Nucleic acid sensing activates the innate cytosolic surveillance pathway and promotes parasite survival in visceral leishmaniasis
por: Das, Sushmita, et al.
Publicado: (2022)

Nucleic acid-sensing toll-like receptors: Important players in Sjögren’s syndrome
por: Alexopoulou, Lena
Publicado: (2022)

Editorial: Broadening our view on nucleic acid sensing: novel sensors, signaling pathways, and involvement in non-infectious diseases
por: Chauveau, Lise, et al.
Publicado: (2023)

Genetic Immunization with CDR3-Based Fusion Vaccine Confers Protection and Long-Term Tumor-Free Survival in a Mouse Model of Lymphoma
por: Iurescia, Sandra, et al.
Publicado: (2010)

Differential Ability of Bovine Antimicrobial Cathelicidins to Mediate Nucleic Acid Sensing by Epithelial Cells
por: Baumann, Arnaud, et al.
Publicado: (2017)

Inflammatory Response Against Staphylococcus aureus via Intracellular Sensing of Nucleic Acids in Keratinocytes
por: Ngo, Quang Vinh, et al.
Publicado: (2022)

Therapeutic immunomodulation by rationally designed nucleic acids and nucleic acid nanoparticles
por: Panigaj, Martin, et al.
Publicado: (2023)

A Variety of Nucleic Acid Species Are Sensed by cGAS, Implications for Its Diverse Functions
por: Wang, Dawei, et al.
Publicado: (2022)

Intratumoural immunotherapy: activation of nucleic acid sensing pattern recognition receptors
por: Agrawal, Sudhir, et al.
Publicado: (2019)

Hippo signaling governs cytosolic nucleic acid sensing through YAP/TAZ-mediated TBK1 blockade
por: Zhang, Qian, et al.
Publicado: (2017)

Cytosolic Sensors for Pathogenic Viral and Bacterial Nucleic Acids in Fish
por: Mojzesz, Miriam, et al.
Publicado: (2020)

Cytosolic delivery of nucleic acids: The case of ionizable lipid nanoparticles
por: Schlich, Michele, et al.
Publicado: (2021)

Cancer immunotherapy strategies that target the cGAS-STING pathway
por: Tian, Zhuoying, et al.
Publicado: (2022)

Smart Nanocarriers for the Targeted Delivery of Therapeutic Nucleic Acid for Cancer Immunotherapy
por: Baker, Abu, et al.
Publicado: (2023)

Crucial Role of Nucleic Acid Sensing via Endosomal Toll-Like Receptors for the Defense of Streptococcus pyogenes in vitro and in vivo
por: Hafner, Anna, et al.
Publicado: (2019)

Editorial: Nucleic Acid-Associated Inflammation
por: Laguette, Nadine, et al.
Publicado: (2021)

Delivery of nucleic acid therapeutics for cancer immunotherapy
por: Zhou, Shurong, et al.
Publicado: (2020)

Agonistic Activation of Cytosolic DNA Sensing Receptors in Woodchuck Hepatocyte Cultures and Liver for Inducing Antiviral Effects
por: Suresh, Manasa, et al.
Publicado: (2021)

Targeting cytosolic proliferating cell nuclear antigen in neutrophil-dominated inflammation
por: Chiara, Alessia De, et al.
Publicado: (2012)

Dysregulation in nucleic acid‐sensing pathway genes is associated with cancer patients’ prognosis
por: Yan‐Fei, Huo, et al.
Publicado: (2020)

The cGAS-STING Pathway: A Promising Immunotherapy Target
por: Ou, Liang, et al.
Publicado: (2021)

Nucleic Acid Immunity in the Pathogenesis of Cutaneous Lupus Erythematosus
por: Günther, Claudia
Publicado: (2019)

Sources of Pathogenic Nucleic Acids in Systemic Lupus Erythematosus
por: Mustelin, Tomas, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_1ctjel0tcc751i0ft1tf6c0dgf