Cargando…

Long-Term Culture of Organotypic Hippocampal Slice from Old 3xTg-AD Mouse: An ex vivo Model of Alzheimer’s Disease

OBJECTIVE: Conventional methods for organotypic hippocampal tissue slice culture (OHSC) have shown several disadvantages or limitations regarding age of animals used, duration of culture and difficulty using neurodegenerative models. Therefore, we tried to establish OHSC from old 3xTg-Alzheimer’s di...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jang, Sooah, Kim, Hyunjeong, Kim, Hye-jin, Lee, Su Kyoung, Kim, Eun Woo, Namkoong, Kee, Kim, Eosu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Neuropsychiatric Association 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900409/ https://www.ncbi.nlm.nih.gov/pubmed/29475217 http://dx.doi.org/10.30773/pi.2017.04.02

Ejemplares similares

PT578. Endothelial-monocyte-activating polypeptide-2 (EMAP-2) may be a novel treatment target of Alzheimer’s disease
por: Jang, Sooah, et al.
Publicado: (2016)

Infusion of Plasma from Exercised Mice Ameliorates Cognitive Dysfunction by Increasing Hippocampal Neuroplasticity and Mitochondrial Functions in 3xTg-AD Mice
por: Kim, Tae-Woon, et al.
Publicado: (2020)

Olfactory dysfunction in the 3xTg-AD model of Alzheimer’s disease
por: Mitrano, Darlene A., et al.
Publicado: (2021)

Neuroprotective effects of mild hypoxia in organotypic hippocampal slice cultures
por: Kim, Seh Hyun, et al.
Publicado: (2015)

Systematic Phenotyping and Characterization of the 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Javonillo, Dominic I., et al.
Publicado: (2022)

Dopaminergic dysfunction in the 3xTg-AD mice model of Alzheimer’s disease
por: Gloria, Yesica, et al.
Publicado: (2021)

Sex-dependent alterations in the physiology of entorhinal cortex neurons in old heterozygous 3xTg-AD mice
por: Arsenault, Dany, et al.
Publicado: (2020)

Hippocampal Growth Factor and Myokine Cathepsin B Expression following Aerobic and Resistance Training in 3xTg-AD Mice
por: Pena, Gabriel S., et al.
Publicado: (2020)

Organotypic hippocampal slices, an emerging tool to model synucleinopathies
por: Elfarrash, Sara, et al.
Publicado: (2020)

Gender-Specific Neuroimmunoendocrine Response to Treadmill Exercise in 3xTg-AD Mice
por: Giménez-Llort, Lydia, et al.
Publicado: (2010)

Impaired Spatial Reorientation in the 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Stimmell, Alina C., et al.
Publicado: (2019)

Abnormal whisker movements in the 3xTg‐AD mouse model of Alzheimer's disease
por: Simanaviciute, Ugne, et al.
Publicado: (2022)

Proteomic analysis links alterations of bioenergetics, mitochondria-ER interactions and proteostasis in hippocampal astrocytes from 3xTg-AD mice
por: Dematteis, Giulia, et al.
Publicado: (2020)

Persistent Gliosis Interferes with Neurogenesis in Organotypic Hippocampal Slice Cultures
por: Gerlach, Johannes, et al.
Publicado: (2016)

The Impact of Chemical Fixation on the Microanatomy of Mouse Organotypic Hippocampal Slices
por: Idziak, Agata, et al.
Publicado: (2023)

Intranasal insulin prevents anesthesia-induced hyperphosphorylation of tau in 3xTg-AD mice
por: Chen, Yanxing, et al.
Publicado: (2014)

Temporal and regional progression of Alzheimer’s disease‐like pathology in 3xTg‐AD mice
por: Belfiore, Ramona, et al.
Publicado: (2018)

Neuroprotective Effects of Probiotic-Supplemented Diet on Cognitive Behavior of 3xTg-AD Mice
por: Tan, Chenxi, et al.
Publicado: (2022)

Progressive Vascular Abnormalities in the Aging 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Jullienne, Amandine, et al.
Publicado: (2022)

Neuroprotective effects of bee venom phospholipase A2 in the 3xTg AD mouse model of Alzheimer’s disease
por: Ye, Minsook, et al.
Publicado: (2016)

RAPGEF2 mediates oligomeric Aβ‐induced synaptic loss and cognitive dysfunction in the 3xTg‐AD mouse model of Alzheimer’s disease
por: Jang, You‐Na, et al.
Publicado: (2021)

Age-dependent inverse correlations in CSF and plasma amyloid-β(1–42) concentrations prior to amyloid plaque deposition in the brain of 3xTg-AD mice
por: Cho, Soo Min, et al.
Publicado: (2016)

Genetic Knockdown of Brain-Derived Neurotrophic Factor in 3xTg-AD Mice Does Not Alter Aβ or Tau Pathology
por: Castello, Nicholas A., et al.
Publicado: (2012)

Spatial memory deficiency early in 6xTg Alzheimer’s disease mouse model
por: Kang, Shinwoo, et al.
Publicado: (2021)

A hierarchy of manganese competition and entry in organotypic hippocampal slice cultures
por: Petrus, Emily, et al.
Publicado: (2021)

Treatment of Alzheimer's Disease with Anti-Homocysteic Acid Antibody in 3xTg-AD Male Mice
por: Hasegawa, Tohru, et al.
Publicado: (2010)

DHA Improves Cognition and Prevents Dysfunction of Entorhinal Cortex Neurons in 3xTg-AD Mice
por: Arsenault, Dany, et al.
Publicado: (2011)

Early and sustained altered expression of aging-related genes in young 3xTg-AD mice
por: Gatta, V, et al.
Publicado: (2014)

Reversal of memory and neuropsychiatric symptoms and reduced tau pathology by selenium in 3xTg-AD mice
por: Van der Jeugd, Ann, et al.
Publicado: (2018)

Sex Differences in Healthspan Predict Lifespan in the 3xTg-AD Mouse Model of Alzheimer’s Disease
por: Kane, Alice E., et al.
Publicado: (2018)

Exercise and resveratrol increase fracture resistance in the 3xTg-AD mouse model of Alzheimer’s disease
por: Alkhouli, Mustafa F., et al.
Publicado: (2019)

Enhanced susceptibility of triple transgenic Alzheimer’s disease (3xTg-AD) mice to acute infection
por: Montacute, Rebecca, et al.
Publicado: (2017)

Fingolimod Rescues Memory and Improves Pathological Hallmarks in the 3xTg-AD Model of Alzheimer’s Disease
por: Fagan, Steven G., et al.
Publicado: (2022)

Sexual Dimorphism in the 3xTg-AD Mouse Model and Its Impact on Pre-Clinical Research
por: Dennison, Jessica L., et al.
Publicado: (2021)

Retracted: Neuroprotective Effects of Probiotic-Supplemented Diet on Cognitive Behavior of 3xTg-AD Mice
por: Engineering, Journal of Healthcare
Publicado: (2023)

Endogenous Amyloid-formed Ca(2+)-permeable Channels in Aged 3xTg AD Mice
por: Li, Shuangtao, et al.
Publicado: (2023)

Low-Dose Chidamide Treatment Displays Sex-Specific Differences in the 3xTg-AD Mouse
por: Dennison, Jessica, et al.
Publicado: (2023)

A longitudinal multimodal in vivo molecular imaging study of the 3xTg-AD mouse model shows progressive early hippocampal and taurine loss
por: Chiquita, Samuel, et al.
Publicado: (2019)

Surfactant Protein-G in Wildtype and 3xTg-AD Mice: Localization in the Forebrain, Age-Dependent Hippocampal Dot-like Deposits and Brain Content
por: Meinicke, Anton, et al.
Publicado: (2022)

Neuroprotective effects of CD4(+)CD25(+)Foxp3(+) regulatory T cells in a 3xTg-AD Alzheimer's disease model
por: Baek, Hyunjung, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_esjpjjcpogshcemf99lk9n9750