Cargando…
Advanced Activity-Based Protein Profiling Application Strategies for Drug Development
Drug targets and modes of action remain two of the biggest challenges in drug development. To address these problems, chemical proteomic approaches have been introduced to profile targets in complex proteomes. Activity-based protein profiling (ABPP) is one of a growing number chemical proteomic appr...
Autores principales: | Wang, Shan, Tian, Yu, Wang, Min, Sun, Gui-bo, Sun, Xiao-bo |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900428/ https://www.ncbi.nlm.nih.gov/pubmed/29686618 http://dx.doi.org/10.3389/fphar.2018.00353 |
Ejemplares similares
-
Targets Fishing and Identification of Calenduloside E as Hsp90AB1: Design, Synthesis, and Evaluation of Clickable Activity-Based Probe
por: Wang, Shan, et al.
Publicado: (2018) -
Myricitrin Protects Cardiomyocytes from Hypoxia/Reoxygenation Injury: Involvement of Heat Shock Protein 90
por: Wang, Min, et al.
Publicado: (2017) -
Salvianolic Acid A Ameliorates Arsenic Trioxide-Induced Cardiotoxicity Through Decreasing Cardiac Mitochondrial Injury and Promotes Its Anticancer Activity
por: Zhang, Jing-yi, et al.
Publicado: (2018) -
Calenduloside E Analogues Protecting H9c2 Cardiomyocytes Against H(2)O(2)-Induced Apoptosis: Design, Synthesis and Biological Evaluation
por: Tian, Yu, et al.
Publicado: (2017) -
Ginsenoside Compound K Attenuates Ox-LDL-Mediated Macrophage Inflammation and Foam Cell Formation via Autophagy Induction and Modulating NF-κB, p38, and JNK MAPK Signaling
por: Lu, Shan, et al.
Publicado: (2020)