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DRUID: a pipeline for transcriptome-wide measurements of mRNA stability

Control of messenger RNA (mRNA) stability is an important aspect of gene regulation. The gold standard for measuring mRNA stability transcriptome-wide uses metabolic labeling, biochemical isolation of labeled RNA populations, and high-throughput sequencing. However, difficult normalization procedure...

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Detalles Bibliográficos
Autores principales: Lugowski, Andrew, Nicholson, Beth, Rissland, Olivia S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900561/
https://www.ncbi.nlm.nih.gov/pubmed/29438994
http://dx.doi.org/10.1261/rna.062877.117