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Strong conservation of inbred mouse strain microRNA loci but broad variation in brain microRNAs due to RNA editing and isomiR expression

Diversity in the structure and expression of microRNAs, important regulators of gene expression, arises from SNPs, duplications followed by divergence, production of isomiRs, and RNA editing. Inbred mouse strains and crosses using them are important reference populations for genetic mapping, and as...

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Detalles Bibliográficos
Autores principales: Trontti, Kalevi, Väänänen, Juho, Sipilä, Tessa, Greco, Dario, Hovatta, Iiris
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900563/
https://www.ncbi.nlm.nih.gov/pubmed/29445025
http://dx.doi.org/10.1261/rna.064881.117