Molecular barcoding of viral vectors enables mapping and optimization of mRNA trans-splicing

Genome editing has proven to be highly potent in the generation of functional gene knockouts in dividing cells. In the CNS however, efficient technologies to repair sequences are yet to materialize. Reprogramming on the mRNA level is an attractive alternative as it provides means to perform in situ...

Descripción completa

Detalles Bibliográficos
Autores principales: Davidsson, Marcus, Díaz-Fernández, Paula, Torroba, Marcos, Schwich, Oliver D., Aldrin-Kirk, Patrick, Quintino, Luis, Heuer, Andreas, Wang, Gang, Lundberg, Cecilia, Björklund, Tomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cold Spring Harbor Laboratory Press 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900565/
https://www.ncbi.nlm.nih.gov/pubmed/29386333
http://dx.doi.org/10.1261/rna.063925.117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900565/
https://www.ncbi.nlm.nih.gov/pubmed/29386333
http://dx.doi.org/10.1261/rna.063925.117

Ejemplares similares