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Tau Proteolysis in the Pathogenesis of Tauopathies: Neurotoxic Fragments and Novel Biomarkers

With predictions showing that 131.5 million people worldwide will be living with dementia by 2050, an understanding of the molecular mechanisms underpinning disease is crucial in the hunt for novel therapeutics and for biomarkers to detect disease early and/or monitor disease progression. The metabo...

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Detalles Bibliográficos
Autores principales:	Quinn, James P., Corbett, Nicola J., Kellett, Katherine A. B., Hooper, Nigel M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	IOS Press 2018
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900574/ https://www.ncbi.nlm.nih.gov/pubmed/29630551 http://dx.doi.org/10.3233/JAD-170959

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