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The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis

Enzymes at the phosphoenolpyruvate (PEP)–pyruvate–oxaloacetate or anaplerotic (ANA) node control the metabolic flux to glycolysis, gluconeogenesis, and anaplerosis. Here we used genetic, biochemical, and (13)C isotopomer analysis to characterize the role of the enzymes at the ANA node in intracellul...

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Detalles Bibliográficos
Autores principales: Basu, Piyali, Sandhu, Noor, Bhatt, Apoorva, Singh, Albel, Balhana, Ricardo, Gobe, Irene, Crowhurst, Nicola A., Mendum, Tom A., Gao, Liang, Ward, Jane L., Beale, Michael H., McFadden, Johnjoe, Beste, Dany J. V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900758/
https://www.ncbi.nlm.nih.gov/pubmed/29475946
http://dx.doi.org/10.1074/jbc.RA118.001839