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The anaplerotic node is essential for the intracellular survival of Mycobacterium tuberculosis
Enzymes at the phosphoenolpyruvate (PEP)–pyruvate–oxaloacetate or anaplerotic (ANA) node control the metabolic flux to glycolysis, gluconeogenesis, and anaplerosis. Here we used genetic, biochemical, and (13)C isotopomer analysis to characterize the role of the enzymes at the ANA node in intracellul...
Autores principales: | Basu, Piyali, Sandhu, Noor, Bhatt, Apoorva, Singh, Albel, Balhana, Ricardo, Gobe, Irene, Crowhurst, Nicola A., Mendum, Tom A., Gao, Liang, Ward, Jane L., Beale, Michael H., McFadden, Johnjoe, Beste, Dany J. V. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900758/ https://www.ncbi.nlm.nih.gov/pubmed/29475946 http://dx.doi.org/10.1074/jbc.RA118.001839 |
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