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Homocysteine regulates fatty acid and lipid metabolism in yeast
S-Adenosyl-l-homocysteine hydrolase (AdoHcy hydrolase; Sah1 in yeast/AHCY in mammals) degrades AdoHcy, a by-product and strong product inhibitor of S-adenosyl-l-methionine (AdoMet)-dependent methylation reactions, to adenosine and homocysteine (Hcy). This reaction is reversible, so any elevation of...
Autores principales: | Visram, Myriam, Radulovic, Maja, Steiner, Sabine, Malanovic, Nermina, Eichmann, Thomas O., Wolinski, Heimo, Rechberger, Gerald N., Tehlivets, Oksana |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Biochemistry and Molecular Biology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900771/ https://www.ncbi.nlm.nih.gov/pubmed/29414770 http://dx.doi.org/10.1074/jbc.M117.809236 |
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