Cargando…

Predicting clinical diagnosis in Huntington's disease: An imaging polymarker

OBJECTIVE: Huntington's disease (HD) gene carriers can be identified before clinical diagnosis; however, statistical models for predicting when overt motor symptoms will manifest are too imprecise to be useful at the level of the individual. Perfecting this prediction is integral to the search...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mason, Sarah L., Daws, Richard E., Soreq, Eyal, Johnson, Eileanoir B., Scahill, Rachael I., Tabrizi, Sarah J., Barker, Roger A., Hampshire, Adam
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2018
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900832/ https://www.ncbi.nlm.nih.gov/pubmed/29405351 http://dx.doi.org/10.1002/ana.25171

Ejemplares similares

Dynamics of Cortical Degeneration Over a Decade in Huntington’s Disease
por: Johnson, Eileanoir B., et al.
Publicado: (2021)

A Multi-Study Model-Based Evaluation of the Sequence of Imaging and Clinical Biomarker Changes in Huntington’s Disease
por: Wijeratne, Peter A., et al.
Publicado: (2021)

Diffusion imaging in Huntington’s disease: comprehensive review
por: Estevez-Fraga, Carlos, et al.
Publicado: (2021)

Revealing the Timeline of Structural MRI Changes in Premanifest to Manifest Huntington Disease
por: Wijeratne, Peter A., et al.
Publicado: (2021)

Recommendations for the Use of Automated Gray Matter Segmentation Tools: Evidence from Huntington’s Disease
por: Johnson, Eileanoir B., et al.
Publicado: (2017)

Timing of selective basal ganglia white matter loss in premanifest Huntington’s disease
por: Zeun, Paul, et al.
Publicado: (2022)

Neurofilament light protein in blood predicts regional atrophy in Huntington disease
por: Johnson, Eileanoir B., et al.
Publicado: (2018)

An image‐based model of brain volume biomarker changes in Huntington's disease
por: Wijeratne, Peter A., et al.
Publicado: (2018)

Characterizing White Matter in Huntington's Disease
por: Gregory, Sarah, et al.
Publicado: (2019)

Neuroimaging evidence for a network sampling theory of individual differences in human intelligence test performance
por: Soreq, Eyal, et al.
Publicado: (2021)

Intellectual enrichment and genetic modifiers of cognition and brain volume in Huntington’s disease
por: Papoutsi, Marina, et al.
Publicado: (2022)

PolyMarker: A fast polyploid primer design pipeline
por: Ramirez-Gonzalez, Ricardo H., et al.
Publicado: (2015)

Validating Automated Segmentation Tools in the Assessment of Caudate Atrophy in Huntington’s Disease
por: Mansoor, Nina M., et al.
Publicado: (2021)

Aberrant Striatal Value Representation in Huntington's Disease Gene Carriers 25 Years Before Onset
por: Nair, Akshay, et al.
Publicado: (2021)

Robust Markers and Sample Sizes for Multicenter Trials of Huntington Disease
por: Wijeratne, Peter A., et al.
Publicado: (2020)

Neurofilament light-associated connectivity in young-adult Huntington’s disease is related to neuronal genes
por: McColgan, Peter, et al.
Publicado: (2022)

Testing a longitudinal compensation model in premanifest Huntington’s disease
por: Gregory, Sarah, et al.
Publicado: (2018)

Fronto-striatal circuits for cognitive flexibility in far from onset Huntington’s disease: evidence from the Young Adult Study
por: Langley, Christelle, et al.
Publicado: (2021)

Topological length of white matter connections predicts their rate of atrophy in premanifest Huntington’s disease
por: McColgan, Peter, et al.
Publicado: (2017)

Brain Regions Showing White Matter Loss in Huntington’s Disease Are Enriched for Synaptic and Metabolic Genes
por: McColgan, Peter, et al.
Publicado: (2018)

Cerebrospinal fluid neurogranin and TREM2 in Huntington’s disease
por: Byrne, Lauren M., et al.
Publicado: (2018)

Altered iron and myelin in premanifest Huntington's Disease more than 20 years before clinical onset: Evidence from the cross-sectional HD Young Adult Study
por: Johnson, Eileanoir B., et al.
Publicado: (2021)

Cerebrospinal fluid flow dynamics in Huntington's disease evaluated by phase contrast MRI
por: Rodrigues, Filipe B., et al.
Publicado: (2019)

In vivo characterization of white matter pathology in premanifest huntington's disease
por: Zhang, Jiaying, et al.
Publicado: (2018)

The role of the amygdala during emotional processing in Huntington's disease: From pre-manifest to late stage disease
por: Mason, Sarah L., et al.
Publicado: (2015)

Novel targets for Huntington’s disease: future prospects
por: Mason, Sarah L, et al.
Publicado: (2016)

Kynurenine pathway metabolites in cerebrospinal fluid and blood as potential biomarkers in Huntington's disease
por: Rodrigues, Filipe B., et al.
Publicado: (2021)

Longitudinal evaluation of proton magnetic resonance spectroscopy metabolites as biomarkers in Huntington’s disease
por: Lowe, Alexander J, et al.
Publicado: (2022)

Altered Intracortical T(1)-Weighted/T(2)-Weighted Ratio Signal in Huntington’s Disease
por: Rowley, Christopher D., et al.
Publicado: (2018)

Natural biological variation of white matter microstructure is accentuated in Huntington's disease
por: Gregory, Sarah, et al.
Publicado: (2018)

Neuropsychiatry and White Matter Microstructure in Huntington’s Disease
por: Gregory, Sarah, et al.
Publicado: (2015)

Dynamic network coding of working-memory domains and working-memory processes
por: Soreq, Eyal, et al.
Publicado: (2019)

Forecasting individual progression trajectories in Huntington disease enables more powered clinical trials
por: Koval, Igor, et al.
Publicado: (2022)

Longitudinal functional connectivity changes related to dopaminergic decline in Parkinson’s disease
por: Li, Weihua, et al.
Publicado: (2020)

Test-Retest Reliability of Diffusion Tensor Imaging in Huntington’s Disease
por: Cole, James H., et al.
Publicado: (2014)

Brain-derived neurotrophic factor in cerebrospinal fluid and plasma is not a biomarker for Huntington’s disease
por: Ou, Zhen-Yi Andy, et al.
Publicado: (2021)

Early atrophy of pallidum and accumbens nucleus in Huntington’s disease
por: van den Bogaard, Simon J. A., et al.
Publicado: (2010)

The Negative Relationship between Reasoning and Religiosity Is Underpinned by a Bias for Intuitive Responses Specifically When Intuition and Logic Are in Conflict
por: Daws, Richard E., et al.
Publicado: (2017)

Longitudinal Structural MRI in Neurologically Healthy Adults
por: Gregory, Sarah, et al.
Publicado: (2020)

Problems with Social Cognition and Decision-Making in Huntington’s Disease: Why Is it Important?
por: Mason, Sarah L., et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_pbp8f9pci5jfgusdcfl3hhq2kd