Small Molecules Drive Big Improvements in Immuno‐Oncology Therapies

Immuno‐oncology therapies have the potential to revolutionize the armamentarium of available cancer treatments. To further improve clinical response rates, researchers are looking for novel combination regimens, with checkpoint blockade being used as a backbone of the treatment. This Review highligh...

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Detalles Bibliográficos
Autores principales: Huck, Bayard R., Kötzner, Lisa, Urbahns, Klaus
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900885/
https://www.ncbi.nlm.nih.gov/pubmed/28971564
http://dx.doi.org/10.1002/anie.201707816
Descripción
Sumario:Immuno‐oncology therapies have the potential to revolutionize the armamentarium of available cancer treatments. To further improve clinical response rates, researchers are looking for novel combination regimens, with checkpoint blockade being used as a backbone of the treatment. This Review highlights the significance of small molecules in this approach, which holds promise to provide increased benefit to cancer patients.

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