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A Chimeric NaV1.8 Channel Expression System Based on HEK293T Cell Line

Among the nine voltage-gated sodium channel (NaV) subtypes, NaV1.8 is an attractive therapeutic target for pain. The heterologous expression of recombinant NaV1.8 currents is of particular importance for its electrophysiological and pharmacological studies. However, NaV1.8 expresses no or low-level...

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Detalles Bibliográficos
Autores principales: Zhou, Xi, Zhang, Yunxiao, Tang, Dongfang, Liang, Songping, Chen, Ping, Tang, Cheng, Liu, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5900924/
https://www.ncbi.nlm.nih.gov/pubmed/29686617
http://dx.doi.org/10.3389/fphar.2018.00337