Clinical Significance of TDP-43 Neuropathology in Amyotrophic Lateral Sclerosis

To determine the significance of TAR DNA binding protein 43 kDa (TDP-43) pathology in amyotrophic lateral sclerosis (ALS), we examined the whole brains and spinal cords of 57 patients (35 men; 22 women; mean age 63.3 years; 15 patients with c9orf72-associated ALS [c9ALS]). TDP-43 pathologic burden w...

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Detalles Bibliográficos
Autores principales: Cykowski, Matthew D., Powell, Suzanne Z., Peterson, Leif E., Appel, Joan W., Rivera, Andreana L., Takei, Hidehiro, Chang, Ellen, Appel, Stanley H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901081/
https://www.ncbi.nlm.nih.gov/pubmed/28521037
http://dx.doi.org/10.1093/jnen/nlx025

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