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Chemokines
Chemokines are a family of polypeptides that direct the migration of leukocytestoward a site of infection. They play a major role in autoimmune disease and chemokine receptors have recently been found to mediate HIV-1 fusion. In this short review we examine the role of chemokines in host defence and...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
TheScientificWorldJOURNAL
2007
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901204/ https://www.ncbi.nlm.nih.gov/pubmed/17334613 http://dx.doi.org/10.1100/tsw.2007.6 |
| _version_ | 1783314564285202432 |
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| author | Horuk, Richard |
| author_facet | Horuk, Richard |
| author_sort | Horuk, Richard |
| collection | PubMed |
| description | Chemokines are a family of polypeptides that direct the migration of leukocytestoward a site of infection. They play a major role in autoimmune disease and chemokine receptors have recently been found to mediate HIV-1 fusion. In this short review we examine the role of chemokines in host defence and in the pathophysiology of autoimmune diseases. We conclude by discussing various therapeutic approaches that target chemokine receptors and that could be beneficial in disease. |
| format | Online Article Text |
| id | pubmed-5901204 |
| institution | National Center for Biotechnology Information |
| language | English |
| publishDate | 2007 |
| publisher | TheScientificWorldJOURNAL |
| record_format | MEDLINE/PubMed |
| spelling | pubmed-59012042018-06-03 Chemokines Horuk, Richard ScientificWorldJournal Review Article Chemokines are a family of polypeptides that direct the migration of leukocytestoward a site of infection. They play a major role in autoimmune disease and chemokine receptors have recently been found to mediate HIV-1 fusion. In this short review we examine the role of chemokines in host defence and in the pathophysiology of autoimmune diseases. We conclude by discussing various therapeutic approaches that target chemokine receptors and that could be beneficial in disease. TheScientificWorldJOURNAL 2007-02-19 /pmc/articles/PMC5901204/ /pubmed/17334613 http://dx.doi.org/10.1100/tsw.2007.6 Text en Copyright © 2007 Richard Horuk. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
| spellingShingle | Review Article Horuk, Richard Chemokines |
| title | Chemokines |
| title_full | Chemokines |
| title_fullStr | Chemokines |
| title_full_unstemmed | Chemokines |
| title_short | Chemokines |
| title_sort | chemokines |
| topic | Review Article |
| url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901204/ https://www.ncbi.nlm.nih.gov/pubmed/17334613 http://dx.doi.org/10.1100/tsw.2007.6 |
| work_keys_str_mv | AT horukrichard chemokines |