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Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects

Dementia is a general term for a heterogeneous group of organic neurodegenerative diseases. Cerebrovascular causes account for 20% of cases. OBJECTIVE: To describe the clinical and epidemiological features of individuals aged >60 years diagnosed with vascular dementia (VD) or mixed dementia (MxD)...

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Autores principales: Santos, Marcelo Antônio Oliveira, Bezerra, Lucas Soares, Correia, Carolina da Cunha, Bruscky, Igor Silvestre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Associação de Neurologia Cognitiva e do Comportamento 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901248/
https://www.ncbi.nlm.nih.gov/pubmed/29682232
http://dx.doi.org/10.1590/1980-57642018dn12-010006
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author Santos, Marcelo Antônio Oliveira
Bezerra, Lucas Soares
Correia, Carolina da Cunha
Bruscky, Igor Silvestre
author_facet Santos, Marcelo Antônio Oliveira
Bezerra, Lucas Soares
Correia, Carolina da Cunha
Bruscky, Igor Silvestre
author_sort Santos, Marcelo Antônio Oliveira
collection PubMed
description Dementia is a general term for a heterogeneous group of organic neurodegenerative diseases. Cerebrovascular causes account for 20% of cases. OBJECTIVE: To describe the clinical and epidemiological features of individuals aged >60 years diagnosed with vascular dementia (VD) or mixed dementia (MxD) in a referral hospital for dementia. METHODS: A descriptive, retrospective study was carried out from 2014 to 2017 involving elderly individuals (≥60 years) with VA or MxD. Patients presenting other forms of dementia or in use of medication that mimics cognitive disorders were excluded. The 12-item Neuropsychiatric Inventory was used to assess neuropsychiatric symptoms (NPS). RESULTS: 81.1% of the patients presented NPS and only 15% had two or more symptoms. Apathy was the most frequent NPS (56.6%). There was an association between CDR score 1 or 2 and NPS (OR = 6.16, 95% CI: 1.36-27.9, p = 0.02). CONCLUSION: Most patients had a single symptom, predominantly apathy. There was an association between mild-to-moderate dementia and NPS.
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spelling pubmed-59012482018-04-20 Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects Santos, Marcelo Antônio Oliveira Bezerra, Lucas Soares Correia, Carolina da Cunha Bruscky, Igor Silvestre Dement Neuropsychol Original Article Dementia is a general term for a heterogeneous group of organic neurodegenerative diseases. Cerebrovascular causes account for 20% of cases. OBJECTIVE: To describe the clinical and epidemiological features of individuals aged >60 years diagnosed with vascular dementia (VD) or mixed dementia (MxD) in a referral hospital for dementia. METHODS: A descriptive, retrospective study was carried out from 2014 to 2017 involving elderly individuals (≥60 years) with VA or MxD. Patients presenting other forms of dementia or in use of medication that mimics cognitive disorders were excluded. The 12-item Neuropsychiatric Inventory was used to assess neuropsychiatric symptoms (NPS). RESULTS: 81.1% of the patients presented NPS and only 15% had two or more symptoms. Apathy was the most frequent NPS (56.6%). There was an association between CDR score 1 or 2 and NPS (OR = 6.16, 95% CI: 1.36-27.9, p = 0.02). CONCLUSION: Most patients had a single symptom, predominantly apathy. There was an association between mild-to-moderate dementia and NPS. Associação de Neurologia Cognitiva e do Comportamento 2018 /pmc/articles/PMC5901248/ /pubmed/29682232 http://dx.doi.org/10.1590/1980-57642018dn12-010006 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Santos, Marcelo Antônio Oliveira
Bezerra, Lucas Soares
Correia, Carolina da Cunha
Bruscky, Igor Silvestre
Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects
title Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects
title_full Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects
title_fullStr Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects
title_full_unstemmed Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects
title_short Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects
title_sort neuropsychiatric symptoms in vascular dementia: epidemiologic and clinical aspects
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901248/
https://www.ncbi.nlm.nih.gov/pubmed/29682232
http://dx.doi.org/10.1590/1980-57642018dn12-010006
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