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Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects
Dementia is a general term for a heterogeneous group of organic neurodegenerative diseases. Cerebrovascular causes account for 20% of cases. OBJECTIVE: To describe the clinical and epidemiological features of individuals aged >60 years diagnosed with vascular dementia (VD) or mixed dementia (MxD)...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Associação de Neurologia Cognitiva e do Comportamento
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901248/ https://www.ncbi.nlm.nih.gov/pubmed/29682232 http://dx.doi.org/10.1590/1980-57642018dn12-010006 |
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author | Santos, Marcelo Antônio Oliveira Bezerra, Lucas Soares Correia, Carolina da Cunha Bruscky, Igor Silvestre |
author_facet | Santos, Marcelo Antônio Oliveira Bezerra, Lucas Soares Correia, Carolina da Cunha Bruscky, Igor Silvestre |
author_sort | Santos, Marcelo Antônio Oliveira |
collection | PubMed |
description | Dementia is a general term for a heterogeneous group of organic neurodegenerative diseases. Cerebrovascular causes account for 20% of cases. OBJECTIVE: To describe the clinical and epidemiological features of individuals aged >60 years diagnosed with vascular dementia (VD) or mixed dementia (MxD) in a referral hospital for dementia. METHODS: A descriptive, retrospective study was carried out from 2014 to 2017 involving elderly individuals (≥60 years) with VA or MxD. Patients presenting other forms of dementia or in use of medication that mimics cognitive disorders were excluded. The 12-item Neuropsychiatric Inventory was used to assess neuropsychiatric symptoms (NPS). RESULTS: 81.1% of the patients presented NPS and only 15% had two or more symptoms. Apathy was the most frequent NPS (56.6%). There was an association between CDR score 1 or 2 and NPS (OR = 6.16, 95% CI: 1.36-27.9, p = 0.02). CONCLUSION: Most patients had a single symptom, predominantly apathy. There was an association between mild-to-moderate dementia and NPS. |
format | Online Article Text |
id | pubmed-5901248 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Associação de Neurologia Cognitiva e do Comportamento |
record_format | MEDLINE/PubMed |
spelling | pubmed-59012482018-04-20 Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects Santos, Marcelo Antônio Oliveira Bezerra, Lucas Soares Correia, Carolina da Cunha Bruscky, Igor Silvestre Dement Neuropsychol Original Article Dementia is a general term for a heterogeneous group of organic neurodegenerative diseases. Cerebrovascular causes account for 20% of cases. OBJECTIVE: To describe the clinical and epidemiological features of individuals aged >60 years diagnosed with vascular dementia (VD) or mixed dementia (MxD) in a referral hospital for dementia. METHODS: A descriptive, retrospective study was carried out from 2014 to 2017 involving elderly individuals (≥60 years) with VA or MxD. Patients presenting other forms of dementia or in use of medication that mimics cognitive disorders were excluded. The 12-item Neuropsychiatric Inventory was used to assess neuropsychiatric symptoms (NPS). RESULTS: 81.1% of the patients presented NPS and only 15% had two or more symptoms. Apathy was the most frequent NPS (56.6%). There was an association between CDR score 1 or 2 and NPS (OR = 6.16, 95% CI: 1.36-27.9, p = 0.02). CONCLUSION: Most patients had a single symptom, predominantly apathy. There was an association between mild-to-moderate dementia and NPS. Associação de Neurologia Cognitiva e do Comportamento 2018 /pmc/articles/PMC5901248/ /pubmed/29682232 http://dx.doi.org/10.1590/1980-57642018dn12-010006 Text en https://creativecommons.org/licenses/by/4.0/ This is an Open Access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Original Article Santos, Marcelo Antônio Oliveira Bezerra, Lucas Soares Correia, Carolina da Cunha Bruscky, Igor Silvestre Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects |
title | Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects |
title_full | Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects |
title_fullStr | Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects |
title_full_unstemmed | Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects |
title_short | Neuropsychiatric symptoms in vascular dementia: Epidemiologic and clinical aspects |
title_sort | neuropsychiatric symptoms in vascular dementia: epidemiologic and clinical aspects |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901248/ https://www.ncbi.nlm.nih.gov/pubmed/29682232 http://dx.doi.org/10.1590/1980-57642018dn12-010006 |
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