Use of Low Molecular Weight Heparin and Aminocaproic Acid in Chronic DIC Associated with Prostate Cancer- A Case Report

Disseminated Intravascular Coagulopathy (DIC) is the most common coagulopathy in patients with prostate cancer. Though rare, it could be fatal without treatment. Literature suggests that there is significant activation of fibrinolytic pathway. Pathophysiology of DIC in patients with prostate cancer...

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Detalles Bibliográficos
Autores principales: Shirai, Keisuke, Chaudhary, Uzair B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2007
Materias:
Case Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901267/
https://www.ncbi.nlm.nih.gov/pubmed/17619757
http://dx.doi.org/10.1100/tsw.2007.143
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author Shirai, Keisuke
Chaudhary, Uzair B.
author_facet Shirai, Keisuke
Chaudhary, Uzair B.
author_sort Shirai, Keisuke
collection PubMed
description Disseminated Intravascular Coagulopathy (DIC) is the most common coagulopathy in patients with prostate cancer. Though rare, it could be fatal without treatment. Literature suggests that there is significant activation of fibrinolytic pathway. Pathophysiology of DIC in patients with prostate cancer is not completely understood. We present here a case of chronic DIC in a patient with metastatic androgen independent prostate cancer. His DIC was managed successfully with a combination of aminocaproic acid and low weight molecular heparin. The use of low molecular weight heparin may make management of chronic DIC in prostate cancer more feasible in an out patient setting.
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spelling pubmed-59012672018-06-03 Use of Low Molecular Weight Heparin and Aminocaproic Acid in Chronic DIC Associated with Prostate Cancer- A Case Report Shirai, Keisuke Chaudhary, Uzair B. ScientificWorldJournal Case Study Disseminated Intravascular Coagulopathy (DIC) is the most common coagulopathy in patients with prostate cancer. Though rare, it could be fatal without treatment. Literature suggests that there is significant activation of fibrinolytic pathway. Pathophysiology of DIC in patients with prostate cancer is not completely understood. We present here a case of chronic DIC in a patient with metastatic androgen independent prostate cancer. His DIC was managed successfully with a combination of aminocaproic acid and low weight molecular heparin. The use of low molecular weight heparin may make management of chronic DIC in prostate cancer more feasible in an out patient setting. TheScientificWorldJOURNAL 2007-02-02 /pmc/articles/PMC5901267/ /pubmed/17619757 http://dx.doi.org/10.1100/tsw.2007.143 Text en Copyright © 2007 Keisuke Shirai and Uzair B. Chaudhary. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Study
Shirai, Keisuke
Chaudhary, Uzair B.
Use of Low Molecular Weight Heparin and Aminocaproic Acid in Chronic DIC Associated with Prostate Cancer- A Case Report
title Use of Low Molecular Weight Heparin and Aminocaproic Acid in Chronic DIC Associated with Prostate Cancer- A Case Report
title_full Use of Low Molecular Weight Heparin and Aminocaproic Acid in Chronic DIC Associated with Prostate Cancer- A Case Report
title_fullStr Use of Low Molecular Weight Heparin and Aminocaproic Acid in Chronic DIC Associated with Prostate Cancer- A Case Report
title_full_unstemmed Use of Low Molecular Weight Heparin and Aminocaproic Acid in Chronic DIC Associated with Prostate Cancer- A Case Report
title_short Use of Low Molecular Weight Heparin and Aminocaproic Acid in Chronic DIC Associated with Prostate Cancer- A Case Report
title_sort use of low molecular weight heparin and aminocaproic acid in chronic dic associated with prostate cancer- a case report
topic Case Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901267/
https://www.ncbi.nlm.nih.gov/pubmed/17619757
http://dx.doi.org/10.1100/tsw.2007.143
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