Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders

Amine oxidases (AOs) are ubiquitous enzymes involved in the metabolism of biogenic amines. Copper AOs (Cu-AOs) catalyze the oxidative deamination of primary amine groups of several biogenic amines, such as putrescine, cadaverine, and histamine. In the present review, the effects of a plant amine oxi...

Descripción completa

Detalles Bibliográficos
Autores principales: Masini, Emanuela, Bani, Danielle, Marzocca, Cosimo, Mateescu, Mircea Alexandru, Mannaioni, Pier Francesco, Federico, Rodolfo, Mondovì, Bruno
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2007
Materias:
Review Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901317/
https://www.ncbi.nlm.nih.gov/pubmed/17619775
http://dx.doi.org/10.1100/tsw.2007.139
_version_ 1783314590868701184
author Masini, Emanuela
Bani, Danielle
Marzocca, Cosimo
Mateescu, Mircea Alexandru
Mannaioni, Pier Francesco
Federico, Rodolfo
Mondovì, Bruno
author_facet Masini, Emanuela
Bani, Danielle
Marzocca, Cosimo
Mateescu, Mircea Alexandru
Mannaioni, Pier Francesco
Federico, Rodolfo
Mondovì, Bruno
author_sort Masini, Emanuela
collection PubMed
description Amine oxidases (AOs) are ubiquitous enzymes involved in the metabolism of biogenic amines. Copper AOs (Cu-AOs) catalyze the oxidative deamination of primary amine groups of several biogenic amines, such as putrescine, cadaverine, and histamine. In the present review, the effects of a plant amine oxidase (Cu-AO, histaminase, EC1.4.3.6) purified from pea seedlings in the modulation of IgE-mediated allergic reactions, and in the prevention of cardiac and splachnic postischemic reperfusion damage are reported.
format Online
Article
Text
id pubmed-5901317
institution National Center for Biotechnology Information
language English
publishDate 2007
publisher TheScientificWorldJOURNAL
record_format MEDLINE/PubMed
spelling pubmed-59013172018-06-03 Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders Masini, Emanuela Bani, Danielle Marzocca, Cosimo Mateescu, Mircea Alexandru Mannaioni, Pier Francesco Federico, Rodolfo Mondovì, Bruno ScientificWorldJournal Review Article Amine oxidases (AOs) are ubiquitous enzymes involved in the metabolism of biogenic amines. Copper AOs (Cu-AOs) catalyze the oxidative deamination of primary amine groups of several biogenic amines, such as putrescine, cadaverine, and histamine. In the present review, the effects of a plant amine oxidase (Cu-AO, histaminase, EC1.4.3.6) purified from pea seedlings in the modulation of IgE-mediated allergic reactions, and in the prevention of cardiac and splachnic postischemic reperfusion damage are reported. TheScientificWorldJOURNAL 2007-06-12 /pmc/articles/PMC5901317/ /pubmed/17619775 http://dx.doi.org/10.1100/tsw.2007.139 Text en Copyright © 2007 Emanuela Masini et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Masini, Emanuela
Bani, Danielle
Marzocca, Cosimo
Mateescu, Mircea Alexandru
Mannaioni, Pier Francesco
Federico, Rodolfo
Mondovì, Bruno
Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders
title Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders
title_full Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders
title_fullStr Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders
title_full_unstemmed Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders
title_short Pea Seedling Histaminase as a Novel Therapeutic Approach to Anaphylactic and Inflammatory Disorders
title_sort pea seedling histaminase as a novel therapeutic approach to anaphylactic and inflammatory disorders
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901317/
https://www.ncbi.nlm.nih.gov/pubmed/17619775
http://dx.doi.org/10.1100/tsw.2007.139
work_keys_str_mv AT masiniemanuela peaseedlinghistaminaseasanoveltherapeuticapproachtoanaphylacticandinflammatorydisorders
AT banidanielle peaseedlinghistaminaseasanoveltherapeuticapproachtoanaphylacticandinflammatorydisorders
AT marzoccacosimo peaseedlinghistaminaseasanoveltherapeuticapproachtoanaphylacticandinflammatorydisorders
AT mateescumirceaalexandru peaseedlinghistaminaseasanoveltherapeuticapproachtoanaphylacticandinflammatorydisorders
AT mannaionipierfrancesco peaseedlinghistaminaseasanoveltherapeuticapproachtoanaphylacticandinflammatorydisorders
AT federicorodolfo peaseedlinghistaminaseasanoveltherapeuticapproachtoanaphylacticandinflammatorydisorders
AT mondovibruno peaseedlinghistaminaseasanoveltherapeuticapproachtoanaphylacticandinflammatorydisorders

Ejemplares similares