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Retrospective Analysis of Spectrum of Presentation and Treatment Outcome in Extremity Sarcomas: A Single-Centre Experience
INTRODUCTION: The most common site for soft tissue sarcoma is extremity. As complete surgical resection is possible in majority, outcome of this subset is relatively better. There is paucity of data regarding extremity soft tissue sarcoma (STS) from sub-Himalayan and hilly geographical regions. MATE...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901834/ https://www.ncbi.nlm.nih.gov/pubmed/29808079 http://dx.doi.org/10.1155/2018/4350634 |
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author | Bansal, Saurabh Das, Kunal Jain, Navneet Nautiyal, Vipul Gupta, Meenu Shirazi, Nadia Verma, Sanjiv Ahmad, Mushtaq Saini, Sunil |
author_facet | Bansal, Saurabh Das, Kunal Jain, Navneet Nautiyal, Vipul Gupta, Meenu Shirazi, Nadia Verma, Sanjiv Ahmad, Mushtaq Saini, Sunil |
author_sort | Bansal, Saurabh |
collection | PubMed |
description | INTRODUCTION: The most common site for soft tissue sarcoma is extremity. As complete surgical resection is possible in majority, outcome of this subset is relatively better. There is paucity of data regarding extremity soft tissue sarcoma (STS) from sub-Himalayan and hilly geographical regions. MATERIALS AND METHODS: Retrospective analysis was done for extremity STS visiting the study center over a period of 5 years. Data were collected and analyzed for demography, disease characteristics, treatment modalities, and outcome. RESULT: Extremity STS constituted 32.8% of all STS enlisted. Most common subtype noted was pleomorphic STS. Metastatic disease at presentation was noted among 7/43 cases with lung being the most common metastasis site. Wide local excision was done in 37 cases while amputation was required in 5 cases. Adjuvant radiotherapy was given in 27 cases while 18 cases received adjuvant chemotherapy. At median follow-up of 47 months, the overall survival and event-free survival were noted as 47.64% and 41.49%, respectively. CONCLUSION: This study depicts single-center experience of extremity STS. The population analyzed was from sub-Himalayan region with significant lost to follow-up. Pooling of data from different centers has been advocated to derive conclusive results. |
format | Online Article Text |
id | pubmed-5901834 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-59018342018-05-28 Retrospective Analysis of Spectrum of Presentation and Treatment Outcome in Extremity Sarcomas: A Single-Centre Experience Bansal, Saurabh Das, Kunal Jain, Navneet Nautiyal, Vipul Gupta, Meenu Shirazi, Nadia Verma, Sanjiv Ahmad, Mushtaq Saini, Sunil Sarcoma Research Article INTRODUCTION: The most common site for soft tissue sarcoma is extremity. As complete surgical resection is possible in majority, outcome of this subset is relatively better. There is paucity of data regarding extremity soft tissue sarcoma (STS) from sub-Himalayan and hilly geographical regions. MATERIALS AND METHODS: Retrospective analysis was done for extremity STS visiting the study center over a period of 5 years. Data were collected and analyzed for demography, disease characteristics, treatment modalities, and outcome. RESULT: Extremity STS constituted 32.8% of all STS enlisted. Most common subtype noted was pleomorphic STS. Metastatic disease at presentation was noted among 7/43 cases with lung being the most common metastasis site. Wide local excision was done in 37 cases while amputation was required in 5 cases. Adjuvant radiotherapy was given in 27 cases while 18 cases received adjuvant chemotherapy. At median follow-up of 47 months, the overall survival and event-free survival were noted as 47.64% and 41.49%, respectively. CONCLUSION: This study depicts single-center experience of extremity STS. The population analyzed was from sub-Himalayan region with significant lost to follow-up. Pooling of data from different centers has been advocated to derive conclusive results. Hindawi 2018-04-01 /pmc/articles/PMC5901834/ /pubmed/29808079 http://dx.doi.org/10.1155/2018/4350634 Text en Copyright © 2018 Saurabh Bansal et al. http://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Bansal, Saurabh Das, Kunal Jain, Navneet Nautiyal, Vipul Gupta, Meenu Shirazi, Nadia Verma, Sanjiv Ahmad, Mushtaq Saini, Sunil Retrospective Analysis of Spectrum of Presentation and Treatment Outcome in Extremity Sarcomas: A Single-Centre Experience |
title | Retrospective Analysis of Spectrum of Presentation and Treatment Outcome in Extremity Sarcomas: A Single-Centre Experience |
title_full | Retrospective Analysis of Spectrum of Presentation and Treatment Outcome in Extremity Sarcomas: A Single-Centre Experience |
title_fullStr | Retrospective Analysis of Spectrum of Presentation and Treatment Outcome in Extremity Sarcomas: A Single-Centre Experience |
title_full_unstemmed | Retrospective Analysis of Spectrum of Presentation and Treatment Outcome in Extremity Sarcomas: A Single-Centre Experience |
title_short | Retrospective Analysis of Spectrum of Presentation and Treatment Outcome in Extremity Sarcomas: A Single-Centre Experience |
title_sort | retrospective analysis of spectrum of presentation and treatment outcome in extremity sarcomas: a single-centre experience |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901834/ https://www.ncbi.nlm.nih.gov/pubmed/29808079 http://dx.doi.org/10.1155/2018/4350634 |
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