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Characterisation of two Toxoplasma PROPPINs homologous to Atg18/WIPI suggests they have evolved distinct specialised functions

Toxoplasma gondii is a parasitic protist possessing a limited set of proteins involved in the autophagy pathway, a self-degradative machinery for protein and organelle recycling. This distant eukaryote has even repurposed part of this machinery, centered on protein ATG8, for a non-degradative functi...

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Detalles Bibliográficos
Autores principales: Nguyen, Hoa Mai, Liu, Shuxian, Daher, Wassim, Tan, Feng, Besteiro, Sébastien
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901921/
https://www.ncbi.nlm.nih.gov/pubmed/29659619
http://dx.doi.org/10.1371/journal.pone.0195921