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Structures of the Calcium-activated Non-Selective Cation Channel TRPM4

TRPM4 is a calcium-activated, phosphatidylinositol bisphosphate (PtdInsP(2)) modulated, non-selective cation channel, and belongs to the family of melastatin-related transient receptor potential (TRPM) channels. Here we present the cryo-EM structures of the mouse TRPM4 channel with and without ATP....

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Detalles Bibliográficos
Autores principales:	Guo, Jiangtao, She, Ji, Zeng, Weizhong, Chen, Qingfeng, Bai, Xiao-chen, Jiang, Youxing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2017
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5901961/ https://www.ncbi.nlm.nih.gov/pubmed/29211714 http://dx.doi.org/10.1038/nature24997

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