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The Effect of a Nonpeptide Angiotensin II Type 2 Receptor Agonist, Compound 21, on Aortic Aneurysm Growth in a Mouse Model of Marfan Syndrome

INTRODUCTION: Available evidence suggests that the renin–angiotensin–aldosterone (RAA) system is a good target for medical intervention on aortic root dilatation in Marfan syndrome (MFS). The effect of Compound 21 (C21), a nonpeptide angiotensin II type 2 receptor agonist, on aneurysm progression wa...

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Detalles Bibliográficos
Autores principales: Verbrugghe, Peter, Verhoeven, Jelle, Clijsters, Marnick, Vervoort, Dominique, Schepens, Jarne, Meuris, Bart, Herijgers, Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Journal of Cardiovascular Pharmacology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902135/
https://www.ncbi.nlm.nih.gov/pubmed/29300219
http://dx.doi.org/10.1097/FJC.0000000000000560

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