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The Effect of a Nonpeptide Angiotensin II Type 2 Receptor Agonist, Compound 21, on Aortic Aneurysm Growth in a Mouse Model of Marfan Syndrome
INTRODUCTION: Available evidence suggests that the renin–angiotensin–aldosterone (RAA) system is a good target for medical intervention on aortic root dilatation in Marfan syndrome (MFS). The effect of Compound 21 (C21), a nonpeptide angiotensin II type 2 receptor agonist, on aneurysm progression wa...
Autores principales: | Verbrugghe, Peter, Verhoeven, Jelle, Clijsters, Marnick, Vervoort, Dominique, Schepens, Jarne, Meuris, Bart, Herijgers, Paul |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Journal of Cardiovascular Pharmacology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5902135/ https://www.ncbi.nlm.nih.gov/pubmed/29300219 http://dx.doi.org/10.1097/FJC.0000000000000560 |
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